Synthesis of orthogonally protected enantiopure 2,9-diaminodecanedioic acid:: A model for a new general method for the synthesis of orthogonally protected α,α′-diaminodicarboxylic acids

被引：0

作者：

Truchot, C ^{[1
]}

Sasaki, NA ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

HETEROCYCLES | 2004年 / 64卷

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for the synthesis of orthogonally protected enantiopure alpha,alpha'-diaminodicarboxylic acids is described. A key step involves the Julia olefination of an aldehyde and a sulfone, both of which are derived from an optically pure dicarboxylic amino acid such as aspartic and glutamic acid. Straightforward synthesis of orthogonally protected 2,9-diaminodecanedioic acid is chosen to demonstrate the conciseness of this new versatile approach.

引用

页码：393 / 406

页数：14

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