Pd-Catalyzed C(sp3)-H Functionalization/Carbenoid Insertion: All-Carbon Quaternary Centers via Multiple C-C Bond Formation

被引：111
|
作者：
Gutierrez-Bonet, Alvaro [1 ]
Julia-Hernandez, Francisco [1 ]
de Luis, Beatriz [1 ]
Martin, Ruben [1 ,2 ]
机构：
[1] Inst Chem Res Catalonia ICIQ, Av Paisos Catalans 16, Tarragona 43007, Spain
[2] Passeig Lluis Co, Catalan Inst Res & Adv Studies ICREA, Barcelona 08010, Spain
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2016年 / 138卷 / 20期
基金：
欧洲研究理事会;
关键词：
CROSS-COUPLING REACTIONS; H ACTIVATION; DIAZO-COMPOUNDS; ARYLATION; COMPLEXES; MECHANISM; CHLORIDES; ALKANES; ACCESS;
D O I：
10.1021/jacs.6b02867
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Pd-catalyzed C(sp(3))-H functionalization/carbenoid insertion is described. The method allows for the rapid synthesis of bicyclic frameworks, generating all-carbon quaternary centers via multiple C-C bond formations in a straightforward manner.
引用
收藏
页码：6384 / 6387
页数：4
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