Diagnostic and therapeutic management of Cryptococcosis in a kitten with practical considerations to veterinary pediatric therapeutic approach

被引：1
|
作者：
Vercelli, Cristina [1 ]
Peano, Andrea [1 ]
Piovano, Giulia [2 ]
Corona, Antonio [3 ]
Gambino, Graziana [1 ]
Re, Giovanni [1 ]
机构：
[1] Dept Vet Sci Turin, Largo Paolo Braccini 2, I-10095 Grugliasco, Italy
[2] Vet Practitioner, I-10100 Turin, Italy
[3] Vet Clin City Turin, I-10127 Turin, Italy
来源：
MEDICAL MYCOLOGY CASE REPORTS | 2021年 / 32卷
关键词：
Cryptococcus neoformans; Fluconazole; Levetiracetam; Amphotericin B; Drug resistance; FLUCONAZOLE RESISTANCE; CATS; DOGS; NEOFORMANS;
D O I：
10.1016/j.mmcr.2021.04.001
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
A 3-months-old male domestic kitten was referred for repeated seizures. Analysis revealed Cryptococcus neoformans. Levetiracetam and fluconazole were administered without significant clinical improvements and without negativization. Hypothesizing resistance, therapy was switched to amphotericin B. Seizure disappeared. Haematological controls highlighted transitory increasing of CK, BUN, ALP and cholesterol. PCR repeated two weeks after the treatment was negative for Cryptococcus neoformans. Nowadays the cat is 5 years old, and no seizures occurred since the age of 5 months.
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页码：61 / 63
页数：3
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