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- [24] A randomized, double-blind, placebo-controlled, fixed dose-ranging study to assess the efficacy, safety, and tolerability of topiramate oral liquid and sprinkle formulations as an adjunct to concurrent anticonvulsant therapy for infants (1 to 24 months of age, inclusive) with refractory partial onset seizures ANNALS OF NEUROLOGY, 2008, 64 : S118 - S118