Potentiating effect of ecofriendly synthesis of copper oxide nanoparticles using brown alga: antimicrobial and anticancer activities

被引:68
|
作者
Ramaswamy, Sri Vishnu Priya [1 ]
Narendhran, S. [1 ]
Sivaraj, Rajeshwari [1 ]
机构
[1] Karpagam Univ, Sch Life Sci, Environm Nanobiotechnol Lab, Dept Biotechnol, Coimbatore 641021, Tamil Nadu, India
关键词
Antibacterial; anticancer activity; copper oxide nanoparticles; Sargassum polycystum; MARINE NATURAL-PRODUCTS; SILVER NANOPARTICLES; BIOLOGICAL SYNTHESIS; EXTRACTS;
D O I
10.1007/s12034-016-1173-3
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
This study reports the in vitro antimicrobial and anticancer activities of biologically synthesized copper nanoparticles. The antimicrobial activity of green synthesized copper oxide nanoparticles was assessed by well diffusion method. The anticancer activity of brown algae-mediated copper oxide nanoparticles was determined by MTT assay against the cell line (MCF-7). Maximum activity was observed with Pseudomonas aeruginosa and Aspergillus niger. Effective growth inhibition of cells was observed to be more than 93% in antibacterial activity. Thus, the results of the present study indicates that biologically synthesized copper nanoparticles can be used for several diseases, however, it necessitates clinical studies to ascertain their potential as antimicrobial and anticancer agents.
引用
收藏
页码:361 / 364
页数:4
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