Background. Previous research suggests that genetic influences on disordered eating may be greater in pubertal than pre-pubertal girls. Although these findings are consistent with pubertal activation of genetic influences on disordered eating, earlier studies were unable to directly test this hypothesis. The purpose of the present study therefore was to directly examine this possibility by investigating whether pubertal development moderates genetic influences on disordered eating. Method. Participants were 510 female adolescent twins from the Minnesota Twin Family Study. Disordered eating was measured with the Total Score of the Minnesota Eating Behavior Survey, while pubertal status was assessed with the Pubertal Development Scale. Results. Consistent with our hypothesis, model-fitting indicated significant increases in genetic influence on disordered eating with advancing pubertal development. Conclusions. These findings suggest that puberty influences the expression of genes for disordered eating.
机构:
Flinders Univ S Australia, Sch Psychol, POB 2100, Adelaide, SA 5001, AustraliaFlinders Univ S Australia, Sch Psychol, POB 2100, Adelaide, SA 5001, Australia
Fairweather-Schmidt, A. Kate
Wade, Tracey D.
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Flinders Univ S Australia, Sch Psychol, POB 2100, Adelaide, SA 5001, AustraliaFlinders Univ S Australia, Sch Psychol, POB 2100, Adelaide, SA 5001, Australia
机构:
Flinders Univ S Australia, Sch Psychol, Adelaide, SA 5001, AustraliaFlinders Univ S Australia, Sch Psychol, Adelaide, SA 5001, Australia
Wade, Tracey D.
Gordon, Scott
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Queensland Inst Med Res, Dept Genet Epidemiol, Brisbane, Qld 4006, AustraliaFlinders Univ S Australia, Sch Psychol, Adelaide, SA 5001, Australia
Gordon, Scott
Medland, Sarah
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Queensland Inst Med Res, Dept Genet Epidemiol, Brisbane, Qld 4006, AustraliaFlinders Univ S Australia, Sch Psychol, Adelaide, SA 5001, Australia
Medland, Sarah
Bulik, Cynthia M.
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Univ N Carolina, Dept Psychiat, Chapel Hill, NC USA
Univ N Carolina, Dept Nutr, Chapel Hill, NC USAFlinders Univ S Australia, Sch Psychol, Adelaide, SA 5001, Australia
Bulik, Cynthia M.
Heath, Andrew C.
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Washington Univ, Dept Psychiat, St Louis, MO USAFlinders Univ S Australia, Sch Psychol, Adelaide, SA 5001, Australia
Heath, Andrew C.
Montgomery, Grant W.
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Queensland Inst Med Res, Dept Genet Epidemiol, Brisbane, Qld 4006, AustraliaFlinders Univ S Australia, Sch Psychol, Adelaide, SA 5001, Australia
Montgomery, Grant W.
Martin, Nicholas G.
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Queensland Inst Med Res, Dept Genet Epidemiol, Brisbane, Qld 4006, AustraliaFlinders Univ S Australia, Sch Psychol, Adelaide, SA 5001, Australia
机构:
Yale Univ, Dept Radiol & Biomed Imaging, Sch Med, New Haven, CT 06520 USA
NIMH, NIH, Bethesda, MD 20892 USAYale Univ, Dept Radiol & Biomed Imaging, Sch Med, New Haven, CT 06520 USA
Westwater, Margaret L.
Mallard, Travis T.
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Massachusetts Gen Hosp, Psychiat & Neurodev Genet Unit, Boston, MA USA
Harvard Med Sch, Dept Psychiat, Boston, MA USAYale Univ, Dept Radiol & Biomed Imaging, Sch Med, New Haven, CT 06520 USA
Mallard, Travis T.
Warrier, Varun
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Univ Cambridge, Dept Psychiat, Cambridge, England
Univ Cambridge, Dept Psychol, Cambridge, EnglandYale Univ, Dept Radiol & Biomed Imaging, Sch Med, New Haven, CT 06520 USA
Warrier, Varun
Bethlehem, Richard A. I.
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Univ Cambridge, Dept Psychol, Cambridge, EnglandYale Univ, Dept Radiol & Biomed Imaging, Sch Med, New Haven, CT 06520 USA
Bethlehem, Richard A. I.
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Scheinost, Dustin
Grillon, Christian
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NIMH, NIH, Bethesda, MD 20892 USAYale Univ, Dept Radiol & Biomed Imaging, Sch Med, New Haven, CT 06520 USA
Grillon, Christian
Fletcher, Paul C.
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Univ Cambridge, Dept Psychiat, Cambridge, England
Univ Cambridge, Wellcome Trust MRC Inst Metab Sci, Cambridge, EnglandYale Univ, Dept Radiol & Biomed Imaging, Sch Med, New Haven, CT 06520 USA
Fletcher, Paul C.
Seidlitz, Jakob
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Childrens Hosp Philadelphia, Dept Child & Adolescent Psychiat & Behav Sci, Philadelphia, PA USA
Univ Penn, Dept Psychiat, Philadelphia, PA USA
Univ Penn, Lifespan Brain Inst, Childrens Hosp Philadelphia, Philadelphia, PA USAYale Univ, Dept Radiol & Biomed Imaging, Sch Med, New Haven, CT 06520 USA
Seidlitz, Jakob
Ernst, Monique
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NIMH, NIH, Bethesda, MD 20892 USAYale Univ, Dept Radiol & Biomed Imaging, Sch Med, New Haven, CT 06520 USA
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Univ Colorado, Dept Psychol, Boulder, CO 80309 USAUniv Colorado, Dept Psychol, Boulder, CO 80309 USA
Friend, Angela
DeFries, John C.
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Univ Colorado, Dept Psychol, Boulder, CO 80309 USA
Univ Colorado, Inst Behav Genet, Boulder, CO 80309 USAUniv Colorado, Dept Psychol, Boulder, CO 80309 USA
DeFries, John C.
Olson, Richard K.
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Univ Colorado, Dept Psychol, Boulder, CO 80309 USA
Univ Colorado, Inst Behav Genet, Boulder, CO 80309 USAUniv Colorado, Dept Psychol, Boulder, CO 80309 USA