Lipid peroxidation-derived hepatotoxic aldehydes, 4-hydroxy-2E-hexenal in smoked fish meat products

被引:12
|
作者
Munasinghe, DMS
Ichimaru, KI
Ryuno, M
Ueki, N
Matsui, T
Sugamoto, K
Kawahara, S
Sakai, T [1 ]
机构
[1] Miyazaki Univ, Fac Agr, Dept Biochem & Appl Biosci, Miyazaki 8892192, Japan
[2] Miyazaki Univ, Fac Engn, Dept Appl Chem, Miyazaki 8892192, Japan
关键词
4-hydroxy-2E-hexenal; lipid peroxidation; smoked fish meat products; wood vinegar;
D O I
10.1046/j.1444-2906.2003.00605.x
中图分类号
S9 [水产、渔业];
学科分类号
0908 ;
摘要
Contents of 4-hydroxy-2E-hexenal (HHE), hepatotoxic aldehydes, in smoked fish meat products (smoked salmon and fish meat sausage) were analyzed. Large differences in these contents between the different samples were observed. Very low levels of HHE were detected in fish meat sausage samples. However, a high level of HHE was observed in one batch of smoked salmon. Changes of HHE contents in yellowtail meat containing cherry and sugi wood vinegar stored at 0degreesC were also analyzed for 7 days. Malonaldehyde (MA) was also analyzed in these samples as an index of the lipid peroxidation level. After 3 or 7 days of storage, HHE contents in both wood vinegar-added samples were significantly higher, but MA contents were significantly lower than those of the control.
引用
收藏
页码:189 / 194
页数:6
相关论文
共 50 条
  • [31] Detection of Lipid Peroxidation-Induced DNA Adducts Caused by 4-Oxo-2(E)-nonenal and 4-Oxo-2(E)-hexenal in Human Autopsy Tissues
    Chou, Pei-Hsin
    Kageyama, Shinji
    Matsuda, Shun
    Kanemoto, Keishi
    Sasada, Yoshiaki
    Oka, Megumi
    Shinmura, Kazuya
    Mori, Hiroki
    Kawai, Kazuaki
    Kasai, Hiroshi
    Sugimura, Haruhiko
    Matsuda, Tomonari
    CHEMICAL RESEARCH IN TOXICOLOGY, 2010, 23 (09) : 1442 - 1448
  • [32] LIPID-PEROXIDATION AND CELLULAR-DAMAGE CAUSED BY THE PYRROLIZIDINE ALKALOID SENECIONINE, THE ALKENAL TRANS-4-HYDROXY-2-HEXENAL, AND RELATED ALKENALS
    GRIFFIN, DS
    SEGALL, HJ
    CELL BIOLOGY AND TOXICOLOGY, 1987, 3 (04) : 379 - 390
  • [33] EFFECTS OF THE LIPID-PEROXIDATION PRODUCT (E)-4-HYDROXY-2-NONENAL ON RAM SPERM FUNCTION
    WINDSOR, DP
    WHITE, IG
    SELLEY, ML
    SWAN, MA
    JOURNAL OF REPRODUCTION AND FERTILITY, 1993, 99 (02): : 359 - 366
  • [34] Formation and degradation of aldehydic lipid peroxidation product, (E)-4-hydroxy-2-nonenal in biological system
    Sano, M
    Tomita, I
    JAPANESE JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH, 1996, 42 (03): : 210 - 222
  • [35] Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal
    Doorn, JA
    Petersen, DR
    CHEMICAL RESEARCH IN TOXICOLOGY, 2002, 15 (11) : 1445 - 1450
  • [36] Inhibition of glucose-induced insulin secretion by 4-hydroxy-2-nonenal and other lipid peroxidation products
    Miwa, I
    Ichimura, N
    Sugiura, M
    Hamada, Y
    Taniguchi, S
    ENDOCRINOLOGY, 2000, 141 (08) : 2767 - 2772
  • [37] Postischemic accumulation of lipid peroxidation products in the rat brain: immunohistochemical detection of 4-hydroxy-2-nonenal modified proteins
    Yoshino, H
    Hattori, N
    Urabe, T
    Uchida, K
    Tanaka, M
    Mizuno, Y
    BRAIN RESEARCH, 1997, 767 (01) : 81 - 86
  • [38] Effects of the lipid peroxidation products 4-hydroxy-2-nonenal and malondialdehyde on the proliferation and morphogenetic development of in vitro plant cells
    Adams, LK
    Benson, EE
    Staines, HJ
    Bremner, DH
    Millam, S
    Deighton, N
    JOURNAL OF PLANT PHYSIOLOGY, 1999, 155 (03) : 376 - 386
  • [39] Synthesis of the lipid peroxidation product 4-hydroxy-2(E)-nonenal with 13C stable isotope incorporation
    Jouanin, I.
    Sreevani, V.
    Rathahao, E.
    Gueraud, F.
    Paris, A.
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2008, 51 (1-2): : 87 - 92
  • [40] Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation
    West, JD
    Ji, CA
    Duncan, ST
    Amarnath, V
    Schneider, C
    Rizzo, CJ
    Brash, AR
    Marnettt, LJ
    CHEMICAL RESEARCH IN TOXICOLOGY, 2004, 17 (04) : 453 - 462