Catalytic Synthesis and Stereostructure of 1,2,3-Trisubstituted Decahydroisoquinolines

被引：0
|
作者：
Reshetov, P. V. [1 ]
Seller, R. V. [1 ]
Golikov, A. G. [1 ]
Skuratova, M. I. [1 ]
机构：
[1] Razumovskii Saratov Med Univ, Ul B Kazachya 112, Saratov 410012, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 53卷 / 02期
关键词：
C-13; MAGNETIC-RESONANCE; SEMIEMPIRICAL METHODS; PARAMETERS; OPTIMIZATION; DERIVATIVES;
D O I：
10.1134/S1070428017020130
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Liquid-phase catalytic reduction of 1,2,3-substituted 5,6,7,8-tetrahydroisoquinolinium perchlorates was investigated. The reaction proceeds stereodirectionally affording cis-decahydroisoquinolines. The probable scheme of reaction products formation is suggested. The structure of compounds obtained was established by IR and C-13 NMR spectroscopy.
引用
收藏
页码：222 / 225
页数：4
相关论文
共 50 条
  • [31] Asymmetric synthesis of 1,2,3-trisubstituted cyclopentanes and cyclohexanes as key components of substance P antagonists
    Kuethe, JT
    Wong, A
    Wu, J
    Davies, IW
    Dormer, PG
    Welch, CJ
    Hillier, MC
    Hughes, DL
    Reider, PJ
    JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (17): : 5993 - 6000
  • [32] SYNTHESIS OF DETOMIDINE AND MEDETOMIDINE METABOLITES - 1,2,3-TRISUBSTITUTED ARENES WITH 4'(5')-IMIDAZOLYLMETHYL GROUPS
    STOILOV, I
    WATT, DS
    GOODMAN, JP
    STPYREK, J
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1993, 30 (06) : 1645 - 1651
  • [33] Preparation of 1,2,3-trisubstituted cyclopentadienes and tetrahydroindene derivatives from zirconacyclopentenes
    Takahashi, T
    Xi, ZF
    Kotora, M
    Xi, CJ
    Nakajima, K
    TETRAHEDRON LETTERS, 1996, 37 (42) : 7521 - 7524
  • [34] A palladium-catalyzed route to chiral 1,2,3-trisubstituted cyclopropanes
    Michelet, V
    Genet, JP
    BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE, 1996, 133 (09): : 881 - 889
  • [35] SYNTHESIS OF 1,2,3-TRISUBSTITUTED AND 1,2,2,3-TETRASUBSTITUTED AZIRIDINES FROM ALPHA-CHLOROKETIMINES
    DEKIMPE, N
    MOENS, L
    TETRAHEDRON, 1990, 46 (08) : 2965 - 2974
  • [36] Synthesis and cytotoxic evaluation of 1,2,3-trisubstituted 2-(2-oxoalkyl)-2,3-dihydrobenzimidazoles
    Statkova-Abeghe, Stela
    Ivanova, Iliyan
    Daskalova, Sasha
    Dzhambazov, Balik
    MEDICINAL CHEMISTRY RESEARCH, 2005, 14 (8-9) : 429 - 439
  • [37] Synthesis of optically active 1,2,3-trisubstituted azetidines employing an organocatalytic approach with L-proline
    Amongero, Marcela
    Kaufman, Teodoro S.
    TETRAHEDRON LETTERS, 2013, 54 (15) : 1924 - 1927
  • [38] First Example of Highly Stereoselective Synthesis of 1,2,3-Trisubstituted Cyclopropanes via Chiral Selenonium Ylides
    Wang, Hai-Yang
    Yang, Fei
    Li, Xin-Liang
    Yan, Xue-Ming
    Huang, Zhi-Zhen
    CHEMISTRY-A EUROPEAN JOURNAL, 2009, 15 (15) : 3784 - 3789
  • [39] Synthesis and Cytotoxic Evaluation of 1,2,3-Trisubstituted 2-(2-Oxoalkyl)-2,3-dihydrobenzimidazoles
    Stela Statkova-Abeghe
    Iliyan Ivanov
    Sasha Daskalova
    Balik Dzhambazov
    Medicinal Chemistry Research, 2005, 14 : 429 - 439
  • [40] Directed addition of sulfur-stabilised carbanions to 1,2,3-trisubstituted aziridines
    Craig, Donald
    Lu, Pengfei
    Mathie, Tanya
    Tholen, Niels T. H.
    TETRAHEDRON, 2010, 66 (33) : 6376 - 6382
12345