Is tissue plasminogen activator a threat to neurons?

被引：26
|
作者：
Traynelis, SF [1 ]
Lipton, SA
机构：
[1] Emory Univ, Dept Pharmacol, Atlanta, GA 30322 USA
[2] Burnham Inst, Ctr Neurosci & Aging, La Jolla, CA USA
来源：
NATURE MEDICINE | 2001年 / 7卷 / 01期
关键词：
D O I：
10.1038/83289
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The clot-busting drug tissue plasminogen activator (tPA) is currently the only FDA-approved therapy for acute stroke. However, increasing evidence suggests that tPA can also contribute to excitotoxic neuronal damage in animal models of stroke.
引用
收藏
页码：17 / 18
页数：2
相关论文
共 50 条
12345