Pharmacological safety testing on iPSC derived cardiomyocytes using the patch clamp and the Microelectrode Array (MEA) technique

被引:0
|
作者
Loser, D. [1 ,2 ]
Danker, T. [2 ]
Moeller, C. [1 ]
Kraushaar, U. [3 ]
机构
[1] Albstadt Sigmaringen Univ, Fac Life Sci, Sigmaringen, Germany
[2] NMI TT GmbH, Reutlingen, Germany
[3] NMI, Reutlingen, Germany
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P44
引用
收藏
页码:S33 / S33
页数:1
相关论文
共 45 条
  • [21] In situ monolayer patch clamp of acutely stimulated human iPSC-derived cardiomyocytes promotes consistent electrophysiological responses to SK channel inhibition
    Andrew S. Butler
    Raimondo Ascione
    Neil V. Marrion
    Stephen C. Harmer
    Jules C. Hancox
    Scientific Reports, 14
  • [22] Toxicity testing and drug screening using iPSC-derived hepatocytes, cardiomyocytes, and neural cells
    Csobonyeiova, Maria
    Polak, Stefan
    Danisovic, L'ubos
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2016, 94 (07) : 687 - 694
  • [23] Assessment of potassium current in Royan B-1 stem cell derived cardiomyocytes by patch-clamp technique
    Sadraei, H.
    Abtahi, S. R.
    Nematollahi, M.
    Karbalaie, K.
    Karamali, F.
    Baharvand, H.
    Nasr-Esfahani, M. H.
    RESEARCH IN PHARMACEUTICAL SCIENCES, 2009, 4 (02) : 85 - 97
  • [24] Automated Patch Clamp System Introducing Simulated IK1 into Stem Cell-Derived Cardiomyocytes using Dynamic Clamp
    Okeyo, George O.
    Horvath, Andras
    Becker, Nadine
    Fabbri, Alan
    Grad, Christian
    George, Michael
    de Boer, Teun P.
    Fertig, Niels
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 571A - 571A
  • [25] Characterization of electrically and optically paced hiPSC-derived cardiomyocytes in vitro using multiwell microelectrode array technology
    Millard, Daniel C.
    Hayes, Heather B.
    de Korte, Tessa
    Wilbers, Rene
    Nicolini, Anthony M.
    Arrowood, Colin A.
    Clements, Mike
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2018, 93 : 116 - 117
  • [26] Establishment of Neurotoxicity Assessment Using Microelectrode Array (MEA) with hiPSC-Derived Neurons and Evaluation of New Psychoactive Substances (NPS)
    Kang, Kyu-ree
    Kim, C-Yoon
    Kim, Jin
    Ryu, Bokyeong
    Lee, Seul-Gi
    Baek, Jieun
    Kim, Ye-Ji
    Lee, Jin-Moo
    Lee, Yootmo
    Choi, Sun-Ok
    Woo, Dong Ho
    Park, Il Hwan
    Chung, Hyung Min
    INTERNATIONAL JOURNAL OF STEM CELLS, 2022, 15 (03) : 258 - 269
  • [27] Automated Patch-Clamp Pharmacology Assays using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
    Scheel, Olaf
    Frech, Stefanie
    Amuzescu, Bogdan P.
    Eisfeld, Joerg
    Lin, Kun-Han
    Knott, Thomas
    BIOPHYSICAL JOURNAL, 2015, 108 (02) : 585A - 585A
  • [28] Predicting cardiac safety using human induced pluripotent stem cell-derived cardiomyocytes combined with multi-electrode array (MEA) technology: A conference report
    Mulder, Petra
    de Korte, Tessa
    Dragicevic, Elena
    Kraushaar, Udo
    Printemps, Richard
    Vlaming, Maria L. H.
    Braam, Stefan R.
    Valentin, Jean-Pierre
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2018, 91 : 36 - 42
  • [29] Pharmacological characterization of the P2X7 receptor on human macrophages using the patch-clamp technique
    Dagmar Eschke
    Melinda Wüst
    Sunna Hauschildt
    Karen Nieber
    Naunyn-Schmiedeberg's Archives of Pharmacology, 2002, 365 : 168 - 171
  • [30] Pharmacological characterization of the P2X7 receptor on human macrophages using the patch-clamp technique
    Eschke, D
    Wüst, M
    Hauschildt, S
    Nieber, K
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2002, 365 (02) : 168 - 171