Identification of carboxyl-terminal phosphorylation sites regulating agonist-induced β-arrestin recruitment and internalization of the human sst3 somatostatin receptor

被引:0
|
作者
Fritzwanker, S. [1 ]
Lehmann, A. [1 ]
Kliewer, A. [1 ]
Guenther, T. [1 ]
Nagel, F. [1 ]
Schulz, S. [1 ]
机构
[1] Univ Hosp Jena, Inst Pharmacol & Toxicol, Jena, Germany
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P14
引用
收藏
页码:S27 / S27
页数:1
相关论文
共 41 条
  • [31] β-Arrestin-2 Interaction and Internalization of the Human P2Y1 Receptor Are Dependent on C-Terminal Phosphorylation Sites
    Reiner, Susanne
    Ziegler, Nicole
    Leon, Catherine
    Lorenz, Kristina
    von Hayn, Kathrin
    Gachet, Christian
    Lohse, Martin J.
    Hoffmann, Carsten
    MOLECULAR PHARMACOLOGY, 2009, 76 (06) : 1162 - 1171
  • [32] Mutations of the second extracellular loop of the human lutropin receptor emphasize the importance of receptor activation and die-emphasize the importance of receptor phosphorylation in agonist-induced internalization
    Li, SH
    Liu, XB
    Min, L
    Ascoli, M
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (11) : 7968 - 7973
  • [33] Somatostatin increases mitogen-induced IL-2 secretion and proliferation of human Jurkat T cells via sst3 receptor isotype
    Cardoso, A
    ElGhamrawy, C
    Gautron, JP
    Horvat, B
    Gautier, N
    Enjalbert, A
    Krantic, S
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1998, 68 (01) : 62 - 73
  • [34] Agonist-induced up-regulation of human somatostatin receptor type 1 is regulated by β-arrestin-1 and requires an essential serine residue in the receptor C-tail
    Ramírez, JL
    Watt, HL
    Rocheville, M
    Kumar, U
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2005, 1669 (02): : 182 - 192
  • [35] Mapping of serine residues in the C-terminal domain of the human EP4 receptor relevant for agonist-induced phosphorylation and sequestration
    Neuschäfer-Rube, F
    Böer, U
    Rehwald, M
    Püschel, GP
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2002, 365 : R20 - R20
  • [36] Innovative Bioluminescence Resonance Energy Transfer Assay Reveals Differential Agonist-Induced D2 Receptor Intracellular Trafficking and Arrestin-3 Recruitment
    De Vries, Luc
    Finana, Frederic
    Cathala, Claudie
    Ronsin, Brice
    Cussac, Didier
    MOLECULAR PHARMACOLOGY, 2019, 96 (03) : 308 - 319
  • [37] Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: Role of the carboxyl terminus in EP4 receptor sequestration
    Desai, S
    April, H
    Nwaneshiudu, C
    Ashby, B
    MOLECULAR PHARMACOLOGY, 2000, 58 (06) : 1279 - 1286
  • [38] Agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: Role of the carboxyl terminus in EP4 receptor sequestration.
    Desai, S
    April, H
    Nwaneshiudu, C
    Ashby, B
    FASEB JOURNAL, 2000, 14 (08): : A1346 - +
  • [39] THREONINE RESIDUES IN THE CARBOXYL-TERMINAL OF HUMAN M3 MUSCARINIC ACETYLCHOLINE-RECEPTOR ARE REQUIRED FOR CARBACHOL-INDUCED RECEPTOR DOWN-REGULATION
    YANG, J
    LOGSDON, CD
    WILLIAMS, JA
    GASTROENTEROLOGY, 1993, 104 (04) : A1068 - A1068
  • [40] The C-terminal domain of the human EP4 receptor confers agonist-induced receptor desensitization in a receptor hybrid with the rat EP3 beta receptor
    NeuschaferRube, F
    Hanecke, K
    Puschel, GP
    FEBS LETTERS, 1997, 415 (02) : 119 - 124