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GFSWeb: A web tool for genome-based identification of proteins from mass spectrometric samples
被引:3
|作者:
Wisz, MS
Suarez, MK
Holmes, MR
Giddings, MC
[1
]
机构:
[1] Univ N Carolina, Dept Microbiol & Immunol, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Dept Biochem Engn, Chapel Hill, NC 27599 USA
关键词:
mass spectrometry;
genome;
peptide mass fingerprint;
web interface;
gene finding;
proteomics;
D O I:
10.1021/pr049879y
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
The interpretation of mass spectrometry data for protein identification has become a vital component of proteomics research. However, since most existing software tools rely on protein databases, their success is limited, especially as the pace of annotation efforts fails to keep pace with sequencing. We present a publicly available, web-based version of a software tool that maps peptide mass fingerprint data directly to their genomic origin, allowing for genome-based, annotation-independent protein identification.
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页码:1292 / 1295
页数:4
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