Luminal Signaling: It's What's on the Inside that Counts

被引：0
|
作者：
Symonds, Jennifer M. [1 ]
Hoffman, Matthew P. [1 ]
机构：
[1] NIDCR, Matrix & Morphogenesis Sect, NIH, Bethesda, MD 20892 USA
来源：
DEVELOPMENTAL CELL | 2014年 / 31卷 / 05期
关键词：
MORPHOGENESIS; TISSUE;
D O I：
10.1016/j.devcel.2014.11.019
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
During organogenesis, FGFs are diffusible communication signals that allow cells to coordinate morphogenesis and establish tissue architecture. Recently in Nature, Durdu et al. (2014) show that epithelial cell clusters secrete FGFs into a microlumen, restricting FGF localization so that participating cells coordinate differentiation and collective migration via luminal signaling.
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页码：519 / 520
页数：2
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