EVALUATION OF RED CURRANTS (RIBES RUBRUM L.), BLACK CURRANTS (RIBES NIGRUM L.), RED AND GREEN GOOSEBERRIES (RIBES UVA-CRISPA) FOR POTENTIAL MANAGEMENT OF TYPE 2 DIABETES AND HYPERTENSION USING IN VITRO MODELS

被引:45
|
作者
Pinto, Marcia Da Silva [2 ]
Kwon, Young-In [1 ]
Apostolidis, Emmanouil [1 ]
Lajolo, Franco Maria [2 ]
Genovese, Maria Ines [2 ]
Shetty, Kalidas [1 ]
机构
[1] Univ Massachusetts, Dept Food Sci, Lab Food Biotechnol, Amherst, MA 01003 USA
[2] Univ Sao Paulo, Lab Quim Bioquim & Biol Mol Alimentos, Dept Alimentos & Nutr Expt, FCF, Sao Paulo, Brazil
关键词
TOTAL ANTIOXIDANT CAPACITY; BLOOD-PRESSURE; ALPHA-AMYLASE; GLUCOSE-TOLERANCE; CHLOROGENIC ACID; PHENOLIC-COMPOUNDS; GLOBAL BURDEN; BERRY FRUITS; PREVENTION; COFFEE;
D O I
10.1111/j.1745-4514.2009.00305.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Red currants (Ribes rubrum L.), black currants (Ribes nigrum L.), red and green gooseberries (Ribes uva-crispa) were evaluated for the total phenolics, antioxidant capacity based on 2, 2-diphenyl-1-picrylhydrazyl radical scavenging assay and functionality such as in vitro inhibition of alpha-amylase, alpha-glucosidase and angiotensin I-converting enzyme (ACE) relevant for potential management of hyperglycemia and hypertension. The total phenolics content ranged from 3.2 (green gooseberries) to 13.5 (black currants) mg/g fruit fresh weight. No correlation was found between total phenolics and antioxidant activity. The major phenolic compounds were quercetin derivatives (black currants and green gooseberries) and chlorogenic acid (red currants and red gooseberries). Red currants had the highest alpha-glucosidase, alpha-amylase and ACE inhibitory activities. Therefore red currants could be good dietary sources with potential antidiabetes and antihypertension functionality to compliment overall dietary management of early stages of type 2 diabetes.
引用
收藏
页码:639 / 660
页数:22
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