An antiviral meliacarpin from leaves of Melia azedarach L.

被引：0
|
作者：
Alché, LE
Ferek, GA
Meo, M
Coto, CE
Maier, MS
机构：
[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Organ, RA-1428 Buenos Aires, DF, Argentina
[2] Univ Buenos Aires, Dept Quim Biol, Fac Ciencias Exactas & Nat, RA-1428 Buenos Aires, DF, Argentina
来源：
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES | 2003年 / 58卷 / 3-4期
关键词：
Melia azedarach L; limonoids; antiviral activity;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 muM and 20 mum for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods.
引用
收藏
页码：215 / 219
页数：5
相关论文
共 50 条
  • [21] A New Steroid Ester from the Leaves of Melia azedarach
    Xinhua Ma
    Fang Zhou
    Yanping Deng
    Kaihui Sun
    Haitao Zhang
    Xianming Zeng
    Yonghong Zhang
    Xiangbin Yu
    Chemistry of Natural Compounds, 2018, 54 : 921 - 925
  • [22] Flavonoid and Lignan Glycosides from the Leaves of Melia Azedarach
    Jin Zeng
    Sheng-Nan Zhang
    Hong-Zhi Song
    Rui-Jing Ma
    Qin-Gang Tan
    Chemistry of Natural Compounds, 2020, 56 : 323 - 324
  • [23] FLAVONOID AND LIGNAN GLYCOSIDES FROM THE LEAVES OF Melia azedarach
    Zeng, Jin
    Zhang, Sheng-Nan
    Song, Hong-Zhi
    Ma, Rui-Jing
    Tan, Qin-Gang
    CHEMISTRY OF NATURAL COMPOUNDS, 2020, 56 (02) : 323 - 324
  • [24] PESTICIDAL ACTIVITY OF AN ISOLATED LIMONOID FROM MELIA AZEDARACH L. FRUITS
    Abdel-Aty, Ahmed S.
    Abdel-Megeed, Ahmed
    JOURNAL OF ANIMAL AND PLANT SCIENCES-JAPS, 2015, 25 (02): : 519 - 527
  • [25] Influence of genotype and explant source on indirect organogenesis by in vitro culture of leaves of Melia azedarach L.
    Vila, SK
    Rey, HY
    Mroginski, LA
    BIOCELL, 2004, 28 (01) : 35 - 41
  • [26] Ecotoxicological evaluation of an aqueous phytoextract of Melia azedarach L.
    Popescu, Vlad Sebastian
    Zhang, Leilei
    Papa, Giulia
    Giuliani, Claudia
    Ribaudo, Giovanni
    Abate, Giulia
    Bulgari, Daniela
    Sweeney, Eileen Mac
    Pucci, Mariachiara
    Bottoni, Martina
    Milani, Fabrizia
    Zizioli, Daniela
    Negri, Ilaria
    Gianoncelli, Alessandra
    Gobbi, Emanuela
    Uberti, Daniela
    Lucini, Luigi
    Memo, Maurizio
    Fico, Gelsomina
    Peron, Gregorio
    Mastinu, Andrea
    SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 950
  • [27] A NEW TRITERPENOID FROM MELIA AZEDARACH (L)
    LEVY, EC
    LAVIE, D
    ISRAEL JOURNAL OF CHEMISTRY, 1969, 7 : P16 - &
  • [28] AN ANTIVIRAL FACTOR FROM MELIA-AZEDARACH L PREVENTS TACARIBE VIRUS ENCEPHALITIS IN MICE
    ANDREI, GM
    LAMPURI, JS
    COTO, CE
    DETORRES, RA
    EXPERIENTIA, 1986, 42 (07): : 843 - 845
  • [29] MELIACINE, AN ANTIVIRAL COMPOUND FROM MELIA-AZEDARACH L, INHIBITS INTERFERON-PRODUCTION
    ANDREI, GM
    COULOMBIE, FC
    COURREGES, MC
    DETORRES, RA
    COTO, CE
    JOURNAL OF INTERFERON RESEARCH, 1990, 10 (05): : 469 - 475
  • [30] New lactoyl glycoside quercetin from Melia azedarach leaves
    J. Y. Salib
    H. N. Michael
    S. I. El-Nogoumy
    Chemistry of Natural Compounds, 2008, 44 : 13 - 15
12345