An antiviral meliacarpin from leaves of Melia azedarach L.

被引：0
|
作者：
Alché, LE
Ferek, GA
Meo, M
Coto, CE
Maier, MS
机构：
[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Organ, RA-1428 Buenos Aires, DF, Argentina
[2] Univ Buenos Aires, Dept Quim Biol, Fac Ciencias Exactas & Nat, RA-1428 Buenos Aires, DF, Argentina
来源：
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES | 2003年 / 58卷 / 3-4期
关键词：
Melia azedarach L; limonoids; antiviral activity;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 muM and 20 mum for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods.
引用
收藏
页码：215 / 219
页数：5
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