Severe diabetic ketoacidosis precipitated by COVID-19 in pediatric patients: Two case reports

Introduction The association of COVID-19 with diabetes mellitus is bidirectional. In one direction, diabetes mellitus is associated with an increased risk of severe COVID-19. In the opposite direction, in patients with COVID-19 new-onset diabetes mellitus, severe diabetic ketoacidosis and severe metabolic complications have been described. Clinical case This report describes two patients with diabetes mellitus who came to our hospital with ketoacidosis resulting from new-onset diabetes mellitus. We describe the clinical course and the management approach during the COVID-19 pandemic. Conclusion COVID-19 is associated with metabolic complications such as severe diabetic ketoacidosis.