Assembly of the 30S ribosomal subunit

被引：100
|
作者：
Culver, GM [1 ]
机构：
[1] Iowa State Univ, Dept Biochem Biophys & Mol Biol, Ames, IA 50011 USA
来源：
BIOPOLYMERS | 2003年 / 68卷 / 02期
关键词：
ribosomes; assembly; 30S subunit; in vitro reconstitution;
D O I：
10.1002/bip.10221
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Ribosomes are large macromolecular complexes responsible for cellular protein synthesis. The smallest known cytoplasmic ribosome is found in prokaryotic cells; these ribosomes are about 2.5 MDa and contain more than 4000 nucleotides of RNA and greater than 50 proteins. These components are distributed into two asymmetric subunits. Recent advances in structural studies of ribosomes and ribosomal subunits have revealed intimate details of the interactions within fully assembled particles. In contrast, many details of how these massive ribonucleoprotein complexes assemble remain elusive. The goal of this review is to discuss some crucial aspects of 30S ribosomal subunit assembly. (C) 2003 Wiley Periodicals, Inc.
引用
收藏
页码：234 / 249
页数：16
相关论文
共 50 条
  • [1] Assembly of the 30S ribosomal subunit
    Williamson, J
    [J]. FASEB JOURNAL, 2004, 18 (08): : C5 - C5
  • [2] Assembly of the 30S ribosomal subunit
    Williamson, James R.
    [J]. QUARTERLY REVIEWS OF BIOPHYSICS, 2005, 38 (04) : 397 - 403
  • [3] Assembly of the 30S ribosomal subunit
    Williamson, JR
    Agalarov, SC
    Funke, P
    Prasad, S
    Stout, CD
    Recht, M
    [J]. BIOPHYSICAL JOURNAL, 2003, 84 (02) : 318A - 318A
  • [4] Interaction of era with the 30S ribosomal subunit: Implications for 30S subunit assembly
    Sharma, MR
    Barat, C
    Wilson, DN
    Booth, TM
    Kawazoe, M
    Hori-Takemoto, C
    Shirouzu, M
    Yokoyama, S
    Fucini, P
    Agrawal, RK
    [J]. MOLECULAR CELL, 2005, 18 (03) : 319 - 329
  • [5] An assembly landscape for the 30S ribosomal subunit
    Megan W. T. Talkington
    Gary Siuzdak
    James R. Williamson
    [J]. Nature, 2005, 438 : 628 - 632
  • [6] An assembly landscape for the 30S ribosomal subunit
    Talkington, MWT
    Siuzdak, G
    Williamson, JR
    [J]. NATURE, 2005, 438 (7068) : 628 - 632
  • [7] Exploring the assembly of the 30S ribosomal subunit
    Trylska, Joanna
    McCammon, J. Andrew
    Brooks, Charles L., III
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [8] A Complex Assembly Landscape for the 30S Ribosomal Subunit
    Sykes, Michael T.
    Williamson, James R.
    [J]. ANNUAL REVIEW OF BIOPHYSICS, 2009, 38 : 197 - 215
  • [9] Structure of the 30S ribosomal subunit
    Wimberly B.T.
    Brodersen D.E.
    Clemons Jr. W.M.
    Morgan-Warren R.J.
    Carter A.P.
    Vonrheln C.
    Hartsch T.
    Ramakrishnan V.
    [J]. Nature, 2000, 407 (6802) : 327 - 339
  • [10] The DnaK chaperone system facilitates 30S ribosomal subunit assembly
    Maki, JA
    Schnobrich, DJ
    Culver, GM
    [J]. MOLECULAR CELL, 2002, 10 (01) : 129 - 138
12345