In this paper a novel method for phylogenetic analysis of H5N1 avian influenza virus has been proposed. At first we provide a mapping of virus protein sequence. Based on this mapping, we propose a new distance measure and make use of the corresponding similarity matrix to construct phylogenic tree without requiring multiple alignment. As an application, we construct phylogenic tree for 123 species of H5N1 avian influenza virus. The phylogeny obtained is generally consistent with evolutionary trees constructed in previous studies.
机构:
St Marys Reg Med Ctr, Sabattus St Internal Med Clin, Lewiston, ME 04240 USASt Marys Reg Med Ctr, Sabattus St Internal Med Clin, Lewiston, ME 04240 USA
Skeik, Nedaa
Jabr, Fadi I.
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机构:
Hlth Associates Peace Harbor, Florence, OR USASt Marys Reg Med Ctr, Sabattus St Internal Med Clin, Lewiston, ME 04240 USA