IL-1-β AND TNF-α PROMOTE MONOCYTE SURVIVAL AND PROLIFERATION THROUGH THE INDUCTION OF GM-CSF EXPRESSION BY RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLASTS

被引：0
|
作者：
Christelle, D. -L. [1 ]
Boutet, M. -A. [2 ]
Chatelais, M. [2 ]
Brion, R. [2 ]
Blanchard, F. [2 ]
Heymann, D. [2 ]
Le Goff, B. [1 ]
机构：
[1] Nantes Univ Hosp, Nantes, France
[2] INSERM UMR 957, Nantes, France
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2014年 / 73卷
关键词：
D O I：
10.1136/annrheumdis-2014-eular.4649
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
THU0524
引用
收藏
页码：364 / 364
页数：1
相关论文
共 50 条
  • [31] Mcl-1 expression contributes to the pathogenesis of rheumatoid arthritis by promoting survival of synovial fibroblasts.
    Liu, HT
    Eksarko, P
    Zander, C
    DaVee, R
    Perlman, H
    Koch, AE
    Haines, K
    Pope, RM
    ARTHRITIS AND RHEUMATISM, 2004, 50 (09): : S654 - S655
  • [32] The role of CM1 on the monocyte of rheumatoid arthritis via the induction of inflammatory cytokines, TNF-α, IL-1α/β, IFN-γ and PGE2
    Bae, Seyeon
    Kang, Jae Seung
    Kim, Hye Min
    Maeng, Hyung Gun
    Kong, Joo Myoung
    Lee, Na Eun
    Lee, Wang Jae
    CYTOKINE, 2009, 48 (1-2) : 117 - 117
  • [33] IL-17 and IL-17F modulate GM-CSF production by lung microvascular endothelial cells stimulated with IL-1β and/or TNF-α
    Numasaki, M
    Tomioka, Y
    Takahashi, H
    Sasaki, H
    IMMUNOLOGY LETTERS, 2004, 95 (02) : 175 - 184
  • [34] Largazole, a class I histone deacetylase inhibitor, enhances TNF-α-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblasts
    Ahmed, Salahuddin
    Riegsecker, Sharayah
    Beamer, Maria
    Rahman, Ayesha
    Bellini, Joseph V.
    Bhansali, Pravin
    Tillekeratne, L. M. Viranga
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2013, 270 (02) : 87 - 96
  • [35] Involvement of thioredoxin in rheumatoid arthritis:: Its costimulatory roles in the TNF-α-induced production of IL-6 and IL-8 from cultured synovial fibroblasts
    Yoshida, S
    Katoh, T
    Tetsuka, T
    Uno, K
    Matsui, N
    Okamoto, T
    JOURNAL OF IMMUNOLOGY, 1999, 163 (01): : 351 - 358
  • [36] GLUCOCORTICOIDS REPRESS GENE-EXPRESSION OF GM-CSF, IL-6 AND NAP-1/IL-8, BUT NOT M-CSF IN HUMAN FIBROBLASTS
    TOBLER, A
    SEITZ, M
    DEWALD, B
    BAGGIOLINI, M
    FEY, MF
    EXPERIMENTAL HEMATOLOGY, 1991, 19 (06) : 511 - 511
  • [37] Epigallocatechin-3-gallate suppresses TNF-α -induced production of MMP-1 and -3 in rheumatoid arthritis synovial fibroblasts
    Hee-Jin Yun
    Wan-Hee Yoo
    Myung-Kwan Han
    Young-Rae Lee
    Jong-Suk Kim
    Sang-Il Lee
    Rheumatology International, 2008, 29 : 23 - 29
  • [38] TNF-α modulates angiopoietin-1 expression in rheumatoid synovial fibroblasts via the NF-κB signalling pathway
    Scott, BB
    Zaratin, PF
    Gilmartin, AG
    Hansbury, MJ
    Colombo, A
    Belpasso, C
    Winkler, JD
    Jackson, JR
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2005, 328 (02) : 409 - 414
  • [39] Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF
    Stefanie Haas
    Rainer H Straub
    Arthritis Research & Therapy, 14
  • [40] The active metabolite of leflunomide, A77 1726, increases proliferation of human synovial fibroblasts in presence of IL-1β and TNF-α
    Magne, D.
    Mezin, F.
    Palmer, G.
    Guerne, P. -A.
    INFLAMMATION RESEARCH, 2006, 55 (11) : 469 - 475
12345