Spontaneous clearance of hepatitis C virus infection post-liver transplantation is associated with rapidly changing quasispecies: A single case report

被引：18
|
作者：
Doughty, AL
Zekry, A
Spencer, JD
Turhan, S
Painter, D
McCaughan, GW
机构：
[1] Royal Prince Alfred Hosp, AW Morrow Gastroenterol & Liver Ctr, Camperdown, NSW 2050, Australia
[2] Royal Prince Alfred Hosp, Dept Anat Pathol, Camperdown, NSW, Australia
[3] Univ Sydney, Dept Infect Dis, Sydney, NSW 2006, Australia
来源：
LIVER TRANSPLANTATION | 2000年 / 6卷 / 05期
关键词：
D O I：
10.1053/jlts.2000.9740
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Hepatitis C virus (HCV) clearance post-liver transplantation is uncommon, This is a case report of a patient who, after liver transplantation, developed cholestatic hepatitis characterized by severe graft dysfunction, in conjunction with high viral load. This was, however, followed by viral clearance and normalization of allograft function. The clinical features of this case and the quasispecies patterns during the illness and the clearance periods are described. In addition, management implications in terms of immunosuppressive therapy are discussed.
引用
收藏
页码：648 / 653
页数：6
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