Direct Synthesis of 1-Arylprop-1-ynes with Calcium Carbide as an Acetylene Source

被引：27

作者：

Gao, Lei ^{[1
]}

Li, Zheng ^{[1
]}

机构：

[1] Northwest Normal Univ, Coll Chem & Chem Engn, Lanzhou 730070, Gansu, Peoples R China

来源：

SYNLETT | 2019年 / 30卷 / 13期

基金：

中国国家自然科学基金;

关键词：

arylpropynes; calcium carbide; tosylhydrazones; aralkynes; FRIEDEL-CRAFTS ALKENYLATION; ONE-POT SYNTHESIS; N-TOSYLHYDRAZONES; INTERNAL ALKYNES; STEREOSELECTIVE-SYNTHESIS; CATALYZED ALLYLATION; TERMINAL ALKYNES; FACILE SYNTHESIS; IONIC LIQUID; DERIVATIVES;

D O I：

10.1055/s-0037-1610718

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple method is described for the synthesis of 1-arylprop-1-ynes directly from aromatic aldehyde p-tosylhydrazones by using calcium carbide as an acetylene source. The salient features of this protocol are its use of a readily available and easily handled source of acetylene, its operational simplicity, its high yield, and its broad substrate scope.

引用

页码：1580 / 1584

页数：5

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