Applying Computational Fluid Dynamics Technology in Bioprocesses

被引：1
|
作者：
Fang, Zhiwu [1 ]
机构：
[1] Syst Qual Design Inc, Newbury Pk, CA USA
来源：
BIOPHARM INTERNATIONAL | 2010年 / 23卷 / 05期
关键词：
LARGE-EDDY SIMULATIONS; DUAL RUSHTON TURBINES; CELL BUBBLE INTERACTIONS; STIRRED VESSEL; MACRO-INSTABILITIES; TRAILING VORTICES; CFD SIMULATIONS; MIXING TIME; MICROSCOPIC VISUALIZATION; PARTICLE DISTRIBUTION;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Computational fluid dynamics (CFD) has been widely applied as a trouble-shooting and Quality by Design (QbD) tool for bioprocess from downstream, to upstream, to fill finish. Part 1 of this article series provided an overview of the technology, and the model setup. Here in part 2, we provide a detailed review of the applications of CFD in cell culture and fermentation processes, including flow characterization, mixing, resuspension, scale-up, and cell damage.
引用
收藏
页码：42 / +
页数：10
相关论文
共 50 条
  • [31] Computational fluid dynamics
    Lax, Peter D.
    JOURNAL OF SCIENTIFIC COMPUTING, 2007, 31 (1-2) : 185 - 193
  • [32] Thermal analysis of water-cooled photovoltaic cell by applying computational fluid dynamics
    Guanghua Wu
    Qiang Liu
    Jun Wang
    Bohua Sun
    Journal of Thermal Analysis and Calorimetry, 2021, 144 : 1741 - 1747
  • [33] Prospective on applying machine learning in computational fluid dynamics (CFD) simulation of metallurgical reactors
    Liu, Yuhong
    Zhang, Jiangshan
    Yang, Shufeng
    Li, Jingshe
    Liu, Qing
    IRONMAKING & STEELMAKING, 2024,
  • [34] Computational Fluid Dynamics Technology and Its Application in Wind Environment Analysis
    Yang Li
    JOURNAL OF URBAN TECHNOLOGY, 2010, 17 (03) : 67 - 81
  • [35] Thermal analysis of water-cooled photovoltaic cell by applying computational fluid dynamics
    Wu, Guanghua
    Liu, Qiang
    Wang, Jun
    Sun, Bohua
    JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2021, 144 (05) : 1741 - 1747
  • [36] Quantum Fluid Dynamics and Quantum Computational Fluid Dynamics
    Lin, C. T.
    Kuo, J. K.
    Yen, T. H.
    JOURNAL OF COMPUTATIONAL AND THEORETICAL NANOSCIENCE, 2009, 6 (05) : 1090 - 1108
  • [37] APPLYING COMPUTATIONAL FLUID DYNAMICS METHODOLOGIES TO HYDRO-DYNAMIC LOADS IN THE SUPPRESSION POOL OF A BWR
    Mauritzson, David
    Perzon, Sven
    Probed, Thomas
    PROCEEDINGS OF THE 26TH INTERNATIONAL CONFERENCE ON NUCLEAR ENGINEERING, 2018, VOL 6B, 2018,
  • [38] Simulation of the airflow characteristic inside a hard disk drive by applying a computational fluid dynamics software
    Saha, Chanchal
    Luong, Huynh Trung
    Aziz, M.H.
    Rattanalert, Tharinan
    World Academy of Science, Engineering and Technology, 2010, 72 : 308 - 313
  • [39] Optimization of the Internal Circulating Fluidized Bed Using Computational Fluid Dynamics Technology
    Du, Xiangxi
    Liu, Muyun
    Sun, Yanhua
    Fluid Dynamics and Materials Processing, 2022, 18 (02): : 303 - 312
  • [40] Optimization of the Internal Circulating Fluidized Bed Using Computational Fluid Dynamics Technology
    Du, Xiangxi
    Liu, Muyun
    Sun, Yanhua
    FDMP-FLUID DYNAMICS & MATERIALS PROCESSING, 2022, 18 (02): : 303 - 312
12345