Acquisition of Multidrug-Resistant Human Immunodeficiency Virus Type 1 Infection in a Patient Taking Preexposure Prophylaxis

被引:32
|
作者
Colby, Donn J. [1 ]
Kroon, Eugene [1 ]
Sacdalan, Carlo [1 ]
Gandhi, Monica [2 ]
Grant, Robert M. [2 ]
Phanuphak, Praphan [1 ]
Ananworanich, Jintanat [3 ,4 ]
Robb, Merlin L. [3 ,4 ]
Phanuphak, Nittaya [1 ]
机构
[1] Thai Red Cross AIDS Res Ctr, Bangkok, Thailand
[2] Univ Calif San Francisco, San Francisco, CA 94143 USA
[3] Walter Reed Army Inst Res, US Mil HIV Res Program, Silver Spring, MD USA
[4] Henry M Jackson Fdn Adv Mil Med, Bethesda, MD USA
基金
美国国家卫生研究院;
关键词
HIV; transmission; preexposure prophylaxis; resistance;
D O I
10.1093/cid/ciy321
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We report a case indicating that acquisition of multidrug-resistant human immunodeficiency (HIV) virus type 1 during preexposure prophylaxis with combination tenofovir disoproxil fumarate and emtricitabine or evolution of resistance after HIV seroconversion remains a risk.
引用
收藏
页码:962 / 964
页数:3
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