Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination

被引：12
|
作者：
Pedersen, Rune M. [1 ]
Bang, Line L. [1 ]
Madsen, Lone W. [1 ]
Sydenham, Thomas V. [1 ]
Johansen, Isik S. [1 ]
Jensen, Thoger G. [1 ]
Justesen, Ulrik S. [1 ]
Andersen, Thomas E. [1 ]
机构：
[1] Univ Southern Denmark, Odense, Denmark
来源：
EMERGING INFECTIOUS DISEASES | 2022年 / 28卷 / 06期
关键词：
D O I：
10.3201/eid2806.220503
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The SARS-CoV-2 Omicron variant BA.2 sublineage is rapidly replacing earlier Omicron lineages, suggesting BA.2 has increased vaccine evasion properties. We measured neutralization titers of authentic BA.1 and BA.2 isolates in serum samples from persons who received the BNT162b2 booster vaccine. All samples neutralized BA.1 and BA.2 at equal median values.
引用
收藏
页码：1274 / 1275
页数：2
相关论文
共 50 条
  • [41] Comparable neutralisation evasion of SARS-CoV-2 omicron subvariants BA.1, BA.2, and BA.3
    Arora, Prerna
    Zhang, Lu
    Rocha, Cheila
    Sidarovich, Anzhalika
    Kempf, Amy
    Schulz, Sebastian
    Cossmann, Anne
    Manger, Bernhard
    Baier, Eva
    Tampe, Bjoern
    Moerer, Onnen
    Dickel, Steffen
    Dopfer-Jablonka, Alexandra
    Jaeck, Hans-Martin
    Behrens, Georg M. N.
    Winkler, Martin S.
    Poehlmann, Stefan
    Hoffmann, Markus
    LANCET INFECTIOUS DISEASES, 2022, 22 (06): : 766 - 767
  • [42] Heterologous mRNA vaccine booster increases neutralization of SARS-CoV-2 Omicron BA.2 variant
    Gen Li
    Zhongcheng Zhou
    Peng Du
    Meixiao Zhan
    Ning Li
    Xinxin Xiong
    Shengjun Tang
    Miao Man
    Daniel T. Baptista-Hon
    Ligong Lu
    Signal Transduction and Targeted Therapy, 7
  • [43] Heterologous mRNA vaccine booster increases neutralization of SARS-CoV-2 Omicron BA.2 variant
    Li, Gen
    Zhou, Zhongcheng
    Du, Peng
    Zhan, Meixiao
    Li, Ning
    Xiong, Xinxin
    Tang, Shengjun
    Man, Miao
    Baptista-Hon, Daniel T.
    Lu, Ligong
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 7 (01)
  • [44] Comparative pathogenicity of SARS-CoV-2 Omicron subvariants including BA.1, BA.2, and BA.5
    Tamura, Tomokazu
    Yamasoba, Daichi
    Oda, Yoshitaka
    Ito, Jumpei
    Kamasaki, Tomoko
    Nao, Naganori
    Hashimoto, Rina
    Fujioka, Yoichiro
    Suzuki, Rigel
    Wang, Lei
    Ito, Hayato
    Kashima, Yukie
    Kimura, Izumi
    Kishimoto, Mai
    Tsuda, Masumi
    Sawa, Hirofumi
    Yoshimatsu, Kumiko
    Yamamoto, Yuki
    Nagamoto, Tetsuharu
    Kanamune, Jun
    Suzuki, Yutaka
    Ohba, Yusuke
    Tabata, Kaori
    Yokota, Isao
    Matsuno, Keita
    Takayama, Kazuo
    Tanaka, Shinya
    Sato, Kei
    Fukuhara, Takasuke
    COMMUNICATIONS BIOLOGY, 2023, 6 (01)
  • [45] Omicron BA.1 neutralizing antibody response following Delta breakthrough infection compared with booster vaccination of BNT162b2
    Shohei Yamamoto
    Kouki Matsuda
    Kenji Maeda
    Yusuke Oshiro
    Natsumi Inamura
    Tetsuya Mizoue
    Maki Konishi
    Junko S. Takeuchi
    Kumi Horii
    Mitsuru Ozeki
    Haruhito Sugiyama
    Hiroaki Mitsuya
    Wataru Sugiura
    Norio Ohmagari
    BMC Infectious Diseases, 23
  • [46] Omicron BA.1 neutralizing antibody response following Delta breakthrough infection compared with booster vaccination of BNT162b2
    Yamamoto, Shohei
    Matsuda, Kouki
    Maeda, Kenji
    Oshiro, Yusuke
    Inamura, Natsumi
    Mizoue, Tetsuya
    Konishi, Maki
    Takeuchi, Junko S.
    Horii, Kumi
    Ozeki, Mitsuru
    Sugiyama, Haruhito
    Mitsuya, Hiroaki
    Sugiura, Wataru
    Ohmagari, Norio
    BMC INFECTIOUS DISEASES, 2023, 23 (01)
  • [47] Limited neutralisation of the SARS-CoV-2 Omicron subvariants BA.1 and BA.2 by convalescent and vaccine serum and monoclonal antibodies
    Wilhelm, Alexander
    Widera, Marek
    Grikscheit, Katharina
    Toptan, Tuna
    Schenk, Barbara
    Pallas, Christiane
    Metzler, Melinda
    Kohmer, Niko
    Hoehl, Sebastian
    Marschalek, Rolf
    Herrmann, Eva
    Helfritz, Fabian A.
    Wolf, Timo
    Goetsch, Udo
    Ciesek, Sandra
    EBIOMEDICINE, 2022, 82
  • [48] BNT162b2 booster after heterologous prime-boost vaccination induces potent neutralizing antibodies and T cell reactivity against SARS-CoV-2 Omicron BA.1 in young adults
    Seidel, Alina
    Zanoni, Michelle
    Gross, Ruediger
    Krnavek, Daniela
    Erdemci-Evin, Suemeyye
    von Maltitz, Pascal
    Albers, Dan P. J.
    Conzelmann, Carina
    Liu, Sichen
    Weil, Tatjana
    Mayer, Benjamin
    Hoffmann, Markus
    Poehlmann, Stefan
    Beil, Alexandra
    Kroschel, Joris
    Kirchhoff, Frank
    Muench, Jan
    Mueller, Janis A.
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [49] Household transmission of SARS-CoV-2 Omicron variant of concern subvariants BA.1 and BA.2 in Denmark
    Frederik Plesner Lyngse
    Carsten Thure Kirkeby
    Matthew Denwood
    Lasse Engbo Christiansen
    Kåre Mølbak
    Camilla Holten Møller
    Robert Leo Skov
    Tyra Grove Krause
    Morten Rasmussen
    Raphael Niklaus Sieber
    Thor Bech Johannesen
    Troels Lillebaek
    Jannik Fonager
    Anders Fomsgaard
    Frederik Trier Møller
    Marc Stegger
    Maria Overvad
    Katja Spiess
    Laust Hvas Mortensen
    Nature Communications, 13
  • [50] Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2
    Hu, Bingjie
    Chan, Jasper Fuk-Woo
    Liu, Huan
    Liu, Yuanchen
    Chai, Yue
    Shi, Jialu
    Shuai, Huiping
    Hou, Yuxin
    Huang, Xiner
    Yuen, Terrence Tsz-Tai
    Yoon, Chaemin
    Zhu, Tianrenzheng
    Zhang, Jinjin
    Li, Wenjun
    Zhang, Anna Jinxia
    Zhou, Jie
    Yuan, Shuofeng
    Zhang, Bao-Zhong
    Yuen, Kwok-Yung
    Chu, Hin
    EMERGING MICROBES & INFECTIONS, 2022, 11 (01) : 2275 - 2287
12345