Mutation-targeted T cell responses in blood from patients with solid tumors prior to treatment and which evolve with clinical benefit from anti-PD-1 therapies

被引：0

作者：

Yuen, Benjamin ^{[1
]}

Yin, Fangfang ^{[2
]}

An, Duo ^{[1
]}

Quach, Boi ^{[1
]}

Guo, Linlin ^{[1
]}

Tan, Joanne ^{[2
]}

Peng, Songming ^{[1
]}

Pan, Zheng ^{[1
]}

Dalmas, Olivier ^{[1
]}

Bao, Robert ^{[1
]}

Jacoby, Kyle ^{[1
]}

Sennino, Barbara ^{[1
]}

Mandl, Stefanie ^{[1
]}

Walters, Matt ^{[2
]}

Jaen, Juan ^{[2
]}

Franzusoff, Alex ^{[1
]}

Yuen, Benjamin ^{[1
]}

机构：

[1] PACT Pharma, San Francisco, CA USA

[2] Arcus Biosci, Hayward, CA USA

来源：

JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2019年 / 7卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

P65

引用

页数：2

共 44 条

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[42] PREDICT1: An observational study for identifying blood biomarkers associated with clinical benefit from carboplatin and pemetrexed (CbP) treatment in patients with non-squamous (NS) non-small cell lung cancer (NSCLC) (CJLSG1201).
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[43] Individualized APC targeting VB10.NEO cancer vaccines induce broad neoepitope-specific CD8 T cell responses in patients with advanced or metastatic solid tumors: interim results from a phase 1/2a trial
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[44] Anti-PD-1 Antibody (Sintilimab) Plus Histone Deacetylase Inhibitor (Chidamide) for the Treatment of Refractory or Relapsed Extranodal Natural Killer/T Cell Lymphoma, Nasal Type (r/r-ENKTL): Preliminary Results from a Prospective, Multicenter, Single-Arm, Phase Ib/II Trial (SCENT)
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