Mutation-targeted T cell responses in blood from patients with solid tumors prior to treatment and which evolve with clinical benefit from anti-PD-1 therapies

被引：0

作者：

Yuen, Benjamin ^{[1
]}

Yin, Fangfang ^{[2
]}

An, Duo ^{[1
]}

Quach, Boi ^{[1
]}

Guo, Linlin ^{[1
]}

Tan, Joanne ^{[2
]}

Peng, Songming ^{[1
]}

Pan, Zheng ^{[1
]}

Dalmas, Olivier ^{[1
]}

Bao, Robert ^{[1
]}

Jacoby, Kyle ^{[1
]}

Sennino, Barbara ^{[1
]}

Mandl, Stefanie ^{[1
]}

Walters, Matt ^{[2
]}

Jaen, Juan ^{[2
]}

Franzusoff, Alex ^{[1
]}

Yuen, Benjamin ^{[1
]}

机构：

[1] PACT Pharma, San Francisco, CA USA

[2] Arcus Biosci, Hayward, CA USA

来源：

JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2019年 / 7卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

P65

引用

页数：2

共 44 条

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ANNALS OF ONCOLOGY, 2016, 27
[2] Anti-PD-1 for patients with leptomeningeal metastasis from advanced solid tumors: Efficacy, safety, and biomarkers of response.
Naidoo, Jarushka
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Hu, Chen
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JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
[3] PD-1 Expression on Intratumoral Regulatory T Cells Is Associated with Lack of Benefit from Anti-PD-1 Therapy in Metastatic Clear-Cell Renal Cell Carcinoma Patients
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Matar, Sayed
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Savla, Varunika
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Gupta, Saurabh
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Motzer, Robert J.
Atkins, Michael B.
McDermott, David F.
Sharpe, Arlene H.
Choueiri, Toni K.
Signoretti, Sabina
CLINICAL CANCER RESEARCH, 2024, 30 (04) : 803 - 813
[4] Safety and efficacy of mutant neoantigen-specific T-cell treatment combined anti-PD-1 therapy in stage IV solid tumors
Song, Qi
Yang, Bo
Sheng, Wei
Zhou, Zishan
Zhang, Tianfu
Qin, Boyu
Ji, Liyan
Li, Pansong
Wang, Dan
Zhang, Xiaoling
Sun, Shengjie
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[5] Receptor occupancy and neo-epitope specific T-cell repertoires in patients with solid tissue tumors following anti-PD-1 therapy
Ashok, Devika
Peng, Songming
Yuen, Benjamin
Walters, Matt
Young, Stephen W.
Seitz, Lisa
CANCER RESEARCH, 2019, 79 (13)
[6] Association Between Skin Reactions and Clinical Benefit in Patients Treated with Anti-PD-1 Treatment for Advanced Non-Small Cell Lung Cancer
Aso, M.
Sugawara, S.
Toi, Y.
Sugisaka, J.
Ono, H.
Aiba, T.
Kawana, S.
Saito, R.
Tsurumi, K.
Ono, K.
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Yamanda, S.
Kimura, Y.
Honda, Y.
JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (10) : S600 - S601
[7] Immune T-cell subpopulations from the peripheral blood of non-small cell lung cancer patients are associated with the efficacy of anti-PD-1 immunotherapy
Rogado, J.
Pozo, F.
Troule, K.
Sanchez-Torres, J. M.
Romero Laorden, N.
Mondejar Solis, R.
Donnay Candil, O.
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Aspa, J.
Al-Shahrour, F.
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Colomer, R.
ANNALS OF ONCOLOGY, 2021, 32 : S999 - S1000
[8] Identifying t cell profiles that associate with clinical response to anti-PD-1 treatment in non-small cell lung carcinoma (NSCLC) patients
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Basak, Edwin A.
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van Brakel, Mandy
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JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
[9] Atypical responses in patients with advanced melanoma, lung cancer, renal-cell carcinoma and other solid tumors treated with anti-PD-1 drugs: A systematic review
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CANCER TREATMENT REVIEWS, 2017, 59 : 71 - 78
[10] COMPREHENSIVE SINGLE CELL SEQUENCING ANALYSIS OF PAIRED TISSUE AND BLOOD SAMPLES FROM HCC PATIENTS TREATED WITH NEOADJUVANT ANTI-PD-1 THERAPY REVEALS TREATMENT-INDUCED CLONAL T CELL DYNAMICS
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Hawkins, Peter
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JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A602 - A602

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