Regulation of angiogenesis by the hemostatic system

被引：6
|
作者：
Pirie-Shepherd, SR [1 ]
机构：
[1] Attenuon LLC, San Diego, CA 92121 USA
来源：
FRONTIERS IN BIOSCIENCE-LANDMARK | 2003年 / 8卷
关键词：
angiogenesis; coagulation; fibrinolysis; endothelium; review;
D O I：
10.2741/998
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In recent years it has become apparent that the hemostatic system has a role to play in regulating angiogenesis. This is achieved by components of the coagulation and fibrinolytic systems regulating proteolysis in the milieu and context of extra cellular matrix and the fibrin clot. It is also an emerging paradigm that cryptic fragments, released by proteolysis from components of the coagulation and fibrinolytic systems, have a role to play in regulating angiogenesis. Presented herein is a brief overview of the regulation of angiogenesis by the hemostatic system.
引用
收藏
页码：D286 / D293
页数：8
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