Antibacterial Activity of Chitosan and the Interpolyelectrolyte Complexes of Poly(acrylic acid)-Chitosan

被引：30
|
作者：
Ortega-Ortiz, Hortensia [1 ]
Gutierrez-Rodriguez, Baltazar [2 ]
Cadenas-Pliego, Gregorio [1 ]
Jimenez, Luis Ibarra [1 ]
机构：
[1] Ctr Invest Quim Aplicada, Saltillo 25253, Coahuila, Mexico
[2] UAdeC, Fac Ciencias Quim, Saltillo 25000, Coahuila, Mexico
来源：
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY | 2010年 / 53卷 / 03期
关键词：
antibacterial activity; chitosan; complexes; poly(acrylic acid); polyelectrolytes; HOST; ACID;
D O I：
10.1590/S1516-89132010000300016
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The antimicrobial activity of chitosan and water soluble interpolyelectrolyte complexes of poly(acrylic acid)chitosan was studied. Chitosans of two different molecular weights were tested at different concentration for 0.5 to 5 g.L(-1) as antimicrobial agents against P. aeruginosa and P. oleovorans. In both cases, the best microbial inhibition was obtained with the concentration of 5 g.L(-1). However, the interpolyelectrolyte complexes of poly(acrylic acid)chitosan with composition phi=2 produced higher antibacterial activity than the two chitosans at the concentration of 0.5 g.L(-1). The NPEC2 complex was more effective than chitosans. This could be attributed to the number of moles of the amino groups of chitosan and the carboxylic acid groups of the interpolyelectrolyte complexes poly(acrylic acid).
引用
收藏
页码：623 / 628
页数：6
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