SEROTONIN-2A HOMODIMERS ARE NEEDED FOR SIGNALLING VIA BOTH PHOSPHOLIPASE A2 AND PHOSPHOLIPASE C IN TRANSFECTED CHO CELLS

被引:0
|
作者
Iglesias, A. [1 ]
Cimadevila, M. [1 ]
Cadavid, M. I. [1 ]
Brea, J. [1 ]
Loza, M. I. [1 ]
机构
[1] Univ Santiago de Compostela, BioFarma Res Grp, Ctr Singular Invest Med Mol & Enfermedades Cron C, Ave Barcelona 22, Santiago De Compostela 15782, Spain
关键词
serotonin 2(A) receptor; phospholipase A(2); phospholipase C; homodimer; crosstalk; minimum functional unit;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P087
引用
收藏
页码:61 / 62
页数:2
相关论文
共 50 条
  • [31] 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter
    Ying Qu
    Nelly Villacreses
    Dennis L. Murphy
    Stanley I. Rapoport
    Psychopharmacology, 2005, 180 : 12 - 20
  • [32] Signalling mechanisms and phospholipase A2 translocation in TNF-α mediated cytoprotection in ischaemia
    Loos, Benjamin
    Smith, Robert M.
    Engelbrecht, Anna-Mart
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2007, 42 : S188 - S188
  • [33] 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter
    Qu, Y
    Villacreses, N
    Murphy, DL
    Rapoport, SI
    PSYCHOPHARMACOLOGY, 2005, 180 (01) : 12 - 20
  • [34] The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2β) in β-cells
    Turk, J
    Ramanadham, S
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2004, 82 (10) : 824 - 832
  • [35] Secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2 in murine bone marrow-derived mast cells
    Fonteh, AN
    Atsumi, G
    LaPorte, T
    Chilton, FH
    JOURNAL OF IMMUNOLOGY, 2000, 165 (05): : 2773 - 2782
  • [36] Secretory phospholipase A2 signalling partly overlaps glutamate-mediated events
    Kolko, M
    de Turco, EBR
    Diemer, NH
    Bazan, NG
    JOURNAL OF NEUROCHEMISTRY, 2002, 81 : 101 - 101
  • [37] Activation of phospholipase C γ 2 in lymphoma cells
    Huynh, MQ
    Wuendisch, T
    Ramaswamy, A
    Neubauer, A
    BLOOD, 2005, 106 (11) : 355A - 355A
  • [38] Neuronal damage by secretory phospholipase A2:: modulation by cytosolic phospholipase A2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture
    Kolko, M
    de Turco, EBR
    Diemer, NH
    Bazan, NG
    NEUROSCIENCE LETTERS, 2003, 338 (02) : 164 - 168
  • [39] Quercetin modulates activities of Taiwan cobra phospholipase A2 via its effects on membrane structure and membrane-bound mode of phospholipase A2
    Chiou, Yi-Ling
    Lin, Shinne-Ren
    Hu, Wan-Ping
    Chang, Long-Sen
    JOURNAL OF BIOSCIENCES, 2012, 37 (02) : 277 - 287
  • [40] The molecular biology of the group VIA Ca2+-independent phospholipase A2
    Ma, ZM
    Turk, J
    PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 67, 2001, 67 : 1 - 33