Antiviral and anti-inflammatory therapies in COVID-19

被引:11
|
作者
Szekanecz Zoltan [1 ]
Bogos Krisztina [2 ]
Constantin Tamas [3 ]
Fullesdi Bela [4 ]
Muller Veronika [5 ]
Rakoczi Eva [1 ]
Varkonyi Istvan [6 ]
Valyi-Nagy Istvan [7 ]
机构
[1] Debreceni Egyet, Altalanos Orvostud Kar, Belgyogyaszati Klin, Reumatol, Debrecen, Hungary
[2] Orszagos Koranyi Pulmonol Int, Budapest, Hungary
[3] Semmelweis Egyet, Altalanos Orvostud Kar, Gyermekgyogyaszati Klin 2, Budapest, Hungary
[4] Debreceni Egyet, Altalanos Orvostud Kar, Aneszteziol & Intenz Terapias Klin, Debrecen, Hungary
[5] Semmelweis Egyet, Altalanos Orvostud Kar, Pulmonol Klin, Budapest, Hungary
[6] Debreceni Egyet, Altalanos Orvostud Kar, Infektol Klin, Debrecen, Hungary
[7] Del Pesti Ctr Korhaz, Orszagos Hematol & Infektol Int, Budapest, Hungary
关键词
novel coronavirus infection (COVID-19); coronavirus; cytokine storm; antiviral treatment; cytokine in-hibition treatment; corticosteroid; interleukin-6; inhibition; Janus kinase inhibition; intravenous immunoglobulin; TOCILIZUMAB; MULTICENTER;
D O I
10.1556/650.2021.32230
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The novel coronavirus infection (COVID-19) places a heavy burden on the health care system and our society. There are three major stages in the disease that fundamentally determine treatment approaches. Phases I?IIA require primarily antiviral treatment. In phases IIB?III, anti-inflammatory treatment is needed accompanied by intensive and supportive care. This recommendation applies only to pharmacotherapy and summarizes the therapeutic options based on the available evidence. It also includes a proposed treatment algorithm.
引用
收藏
页码:643 / 651
页数:9
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