Typical and atypical antipsychotics differentially modulates D2/5-HT2A heterooligomer signaling

被引:0
|
作者
Gomez-Garcia, Laura [1 ]
Gomez, Sonia [1 ]
Isabel Cadavid, Maria [1 ]
Manuel Brea, Jose [1 ]
Isabel Loza, Maria [1 ]
机构
[1] Univ Santiago de Compostela, Grp Biofarma, Santiago De Compostela, Spain
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P036
引用
收藏
页码:44 / 45
页数:2
相关论文
共 50 条
  • [41] Dopamine D2 and 5-hydroxytryptamine 5-HT2A receptors assemble into functionally interacting heteromers
    Borroto-Escuela, Dasiel O.
    Romero-Fernandez, Wilber
    Tarakanov, Alexander O.
    Marcellino, Daniel
    Ciruela, Francisco
    Agnati, Luigi F.
    Fuxe, Kjell
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2010, 401 (04) : 605 - 610
  • [42] Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine
    Kanako Terakado Kimura
    Hidetsugu Asada
    Asuka Inoue
    Francois Marie Ngako Kadji
    Dohyun Im
    Chihiro Mori
    Takatoshi Arakawa
    Kunio Hirata
    Yayoi Nomura
    Norimichi Nomura
    Junken Aoki
    So Iwata
    Tatsuro Shimamura
    Nature Structural & Molecular Biology, 2019, 26 : 121 - 128
  • [43] Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice
    Weisstaub, Noelia V.
    Zhou, Mingming
    Lira, Alena
    Lambe, Evelyn
    Gonzalez-Maeso, Javier
    Hornung, Jean-Pierre
    Sibille, Etienne
    Underwood, Mark
    Itohara, Shigeyoshi
    Dauer, William T.
    Ansorge, Mark S.
    Morelli, Emanuela
    Mann, J. John
    Toth, Miklos
    Aghajanian, George
    Sealfon, Stuart C.
    Hen, Rene
    Gingrich, Jay A.
    SCIENCE, 2006, 313 (5786) : 536 - 540
  • [44] In-vivo assessment of 5-HT2A and 5-HT2C antagonistic properties of newer antipsychotics
    Sánchez, C
    Arnt, J
    BEHAVIOURAL PHARMACOLOGY, 2000, 11 (3-4): : 291 - 298
  • [45] Pharmacokinetics and dopamine D2 and serotonin 5-HT2A receptor occupancy of paliperidone in healthy subjects
    Karlsson, P
    Dencker, E
    Nyberg, S
    Mannaert, E
    Boom, S
    Talluri, K
    Rossenu, S
    Eriksson, B
    Eerdekens, M
    Farde, L
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2005, 15 : S386 - S386
  • [46] New hexahydrocarbazoles and spiro indoles, and their affinity for D2 dopamine and 5-HT2A serotonin receptors
    Fernández, F
    García-Mera, X
    Rodríguez, G
    Urrutia, A
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1999, 47 (07) : 1006 - 1009
  • [47] New arylpiperazine derivatives with high affinity for α1A, D2 and 5-HT2A receptors
    González-Gómez, JC
    Santana, L
    Uriarte, E
    Brea, J
    Villazón, M
    Loza, MI
    De Luca, M
    Rivas, ME
    Montenegro, GY
    Fontenla, JA
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (02) : 175 - 178
  • [48] Sensitization to MDMA locomotor effects and changes in the functionality of 5-HT2A and D2 receptors in mice
    Jose Varela, Maria
    Brea, Jose
    Isabel Loza, Maria
    Maldonado, Rafael
    Robledo, Patricia
    BEHAVIOURAL PHARMACOLOGY, 2011, 22 (04): : 362 - 369
  • [49] Butyrophenone analogues in the carbazole series:: Synthesis and determination of affinities at D2 and 5-HT2a receptors
    Masaguer, CE
    Formoso, E
    Raviña, E
    Tristán, H
    Loza, MI
    Rivas, E
    Fontenla, JA
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (24) : 3571 - 3576
  • [50] Augmantation with D2 antagonists for partial reponders to atypical antipsychotics
    Mazeh, D
    Melamed, Y
    Elizur, A
    EUROPEAN PSYCHIATRY, 2000, 15 : 326S - 326S