Gabapentin in late-onset poststroke seizures

被引:67
|
作者
Alvarez-Sabín, J
Montaner, J
Padró, L
Molina, CA
Rovira, R
Codina, A
Quintana, R
机构
[1] Hosp Gen Valle Hebron, Serv Neurol, Unidad Cerebrovasc, Barcelona, Spain
[2] Hosp Gen Valle Hebron, Dept Neurol, Epilepsy Unit, Barcelona, Spain
关键词
D O I
10.1212/01.WNL.0000038388.57824.B6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Stroke is a frequent cause of epileptic seizures (ES) in adults. The authors evaluated the long-term efficacy and tolerability of gabapentin (900 to 1,800 mg/day) in 71 patients with a first poststroke late ES during a mean follow-up time of 30 months. ES recurred in 18.3% of the patients and side effects were noted in 27 cases (38%), but only two (2.8%) required discontinuation. or early withdrawal. Gabapentin monotherapy was useful and safe for late poststroke ES.
引用
收藏
页码:1991 / 1993
页数:3
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