DURABLE REMISSIONS WITH CONTROL OF CYTOKINE RELEASE SYNDROME (CRS) USING T CELLS EXPRESSING CD19 TARGETED CHIMERIC ANTIGEN RECEPTOR (CAR) CTL019 TO TREAT RELAPSED/REFRACTORY (R/R) ACUTE LYMPHOID LEUKEMIA (ALL)

被引:1
|
作者
Levine, B. L. [1 ,2 ,3 ]
Maude, S. [4 ,5 ,6 ]
Zheng, Z. [1 ,2 ]
Shaw, P. [7 ]
Ambrose, D. [1 ]
Aplenc, R. [5 ,6 ]
Barker, C. [4 ,5 ,6 ]
Barrett, D. [4 ,5 ,6 ]
Brogdon, J. [8 ]
Callahan, C. [5 ,6 ]
Chen, F. [1 ]
Chew, A. [1 ]
Davis, M. M. Suhoski [1 ,2 ]
Fesnak, A. D. [1 ,2 ]
Finklestein, J. [1 ]
Frey, N. [8 ]
Lacey, S. [1 ]
Lamontagne, A. [1 ,2 ]
Lewitt, L. [1 ,2 ]
Loew, A. [8 ]
Marcucci, K. [1 ]
Melenhorst, J. [1 ,2 ]
Motley, L. [5 ,6 ]
Mudambi, M. [5 ,6 ]
Nazimuddin, F. [1 ]
O'Rourke, M. [1 ,2 ]
Porter, D. [3 ]
Rheingold, S. R. [5 ,6 ]
Scholler, J. [1 ]
Tayor, C. [1 ,2 ]
White, C. [5 ,6 ]
Wood, P. [9 ]
Young, R. [1 ]
Teachey, D. T. [4 ,5 ,6 ]
June, C. [1 ,2 ,3 ]
Grupp, S. [3 ,4 ,5 ,6 ]
机构
[1] Univ Penn, Ctr Cellular Immunotherapies, Philadelphia, PA 19104 USA
[2] Univ Penn, Pathol & Lab Med, Philadelphia, PA 19104 USA
[3] Abramson Canc Ctr, Philadelphia, PA USA
[4] Univ Penn, Perelman Sch Med, Dept Pediat, Philadelphia, PA 19104 USA
[5] Childrens Hosp Philadelphia, Div Oncol, Philadelphia, PA 19104 USA
[6] Childrens Hosp Philadelphia, Ctr Childhood Canc Res, Philadelphia, PA 19104 USA
[7] Univ Penn, Biostat & Epidemiol, Philadelphia, PA 19104 USA
[8] Novartis Inst Biomed Res, Cambridge, MA USA
[9] Novartis Pharmaceut, Cell & Gene Therapies Unit, E Hanover, NJ USA
关键词
D O I
10.1016/j.jcyt.2016.03.039
中图分类号
Q813 [细胞工程];
学科分类号
摘要
25
引用
收藏
页码:S14 / S15
页数:2
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