Effect of early oral feeding on length of hospital stay following gastrectomy for gastric cancer: a Japanese multicenter, randomized controlled trial

被引：35

作者：

Shimizu, Nobuyuki ^{[1
]}

Oki, Eiji ^{[2
]}

Tanizawa, Yutaka ^{[3
]}

Suzuki, Yutaka ^{[4
]}

Aikou, Susumu ^{[5
]}

Kunisaki, Chikara ^{[6
]}

Tsuchiya, Takashi ^{[7
]}

Fukushima, Ryoji ^{[8
]}

Doki, Yuichiro ^{[9
]}

Natsugoe, Shoji ^{[10
]}

Nishida, Yasunori ^{[11
]}

Morita, Masaru ^{[12
]}

Hirabayashi, Naoki ^{[13
]}

Hatao, Fumihiko ^{[14
]}

Takahashi, Ikuo ^{[15
]}

Choda, Yasuhiro ^{[16
]}

Iwasaki, Yoshiaki ^{[17
]}

Seto, Yasuyuki ^{[5
]}

机构：

[1] Int Univ Hlth & Welf, Sanno Hosp, Dept Surg, Minato Ku, 8-10-16 Akasaka, Tokyo 1070052, Japan

[2] Kyushu Univ, Grad Sch Med Sci, Dept Surg & Sci, Higashi Ku, 3-1-1 Maidashi, Fukuoka, Fukuoka 8128582, Japan

[3] Shizuoka Canc Ctr, Div Gastr Surg, 1007 Shimonagakubo, Nagaizumi, Shizuoka 4118777, Japan

[4] Int Univ Hlth & Welf Hosp, Dept Gastroenterol Surg & Gen Surg, 537-3 Iguchi, Nasushiobara 3292763, Japan

[5] Univ Tokyo, Grad Sch Med, Dept Gastroenterol Surg, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan

[6] Yokohama City Univ, Gastroenterol Ctr, Dept Surg, Minami Ku,Med Ctr, 4-57 Urafune, Yokohama, Kanagawa 2320024, Japan

[7] Sendai Open Hosp, Dept Gastroenterol Surg & Gen Surg, Miyagino Ku, 5-22-1 Tsurugaya, Sendai, Miyagi 9830824, Japan

[8] Teikyo Univ, Dept Surg, Sch Med, Itabashi Ku, 2-11-1 Kaga, Tokyo 1738606, Japan

[9] Osaka Univ, Grad Sch Med, Dept Gastroenterol Surg, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan

[10] Kagoshima Univ, Grad Sch Med & Dent Sci, Dept Digest Surg Breast & Thyroid Surg, 35-1 Sakuragaoka, Kagoshima 8908544, Japan

[11] Keiyukai Sapporo Hosp, Dept Gastroenterol Surg, Shiroishi Ku, Kital 1 Hondori 14 Cho Me, Sapporo, Hokkaido 0030027, Japan

[12] Kyushu Canc Ctr, Dept Gastroenterol Surg, Minami Ku, 3-1-1 Notame, Fukuoka, Fukuoka 8111395, Japan

[13] Hiroshima City Asa Citizens Hosp, Dept Surg, Kita Ku, 2-1-1 Kabeminami, Hiroshima 7310293, Japan

[14] Tokyo Metropolitan Tama Med Ctr, Dept Surg, 8-29 Musashidai, Fuchu, Tokyo 1838524, Japan

[15] Matsuyama Red Cross Hosp, Dept Surg, 1 Bunkyo Cho, Matsuyama, Ehime 7908524, Japan

[16] Hiroshima City Hiroshima Citizens Hosp, Dept Surg, Naka Ku, 33 Motomachi, Hiroshima 7308518, Japan

[17] Komagome Hosp, Tokyo Metropolitan Canc & Infect Dis Ctr, Dept Surg, Bunkyo Ku, 3-18-22 Honkomagome, Tokyo 1138677, Japan

来源：

SURGERY TODAY | 2018年 / 48卷 / 09期

关键词：

Early oral feeding; Gastrectomy; Multicenter randomized controlled trial; Postoperative hospital stay; Safety; QUALITY-OF-LIFE; ROUX-EN-Y; ENHANCED RECOVERY; DISTAL GASTRECTOMY; BILLROTH-I; SURGERY; NUTRITION; CARCINOMA; RESECTION; QUESTIONNAIRE;

D O I：

10.1007/s00595-018-1665-4

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

This multicenter, randomized controlled study evaluates the safety of early oral feeding following gastrectomy, and its effect on the length of postoperative hospital stay. The subjects of this study were patients who underwent distal gastrectomy (DG) or total gastrectomy (TG) for gastric cancer between January 2014 and December 2015. Patients were randomly assigned to the early oral feeding group (intervention group) or the conventional postoperative management group (control group) for each procedure. We evaluated the length of postoperative hospital stay and the incidence of postoperative complications in each group. No significant differences in length of postoperative stay were found between the intervention and control groups of the patients who underwent DG. The incidence of postoperative complications was significantly greater in the DG intervention group. In contrast, the length of postoperative stay was significantly shorter in the TG intervention group, although the TG group did not attain the established target sample size. Early oral feeding did not shorten the postoperative hospital stay after DG. The higher incidence of postoperative complications precluded the unselected adoption of early oral feeding for DG patients. Further confirmative studies are required to definitively establish the potential benefits of early oral feeding for TG patients.

引用

页码：865 / 874

页数：10

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