The Role of Resveratrol in Human Male Fertility

被引：27
|
作者：
Mongioi, Laura M. [1 ]
Perelli, Sarah [1 ]
Condorelli, Rosita A. [1 ]
Barbagallo, Federica [1 ]
Crafa, Andrea [1 ]
Cannarella, Rossella [1 ]
La Vignera, Sandro [1 ]
Calogero, Aldo E. [1 ]
机构：
[1] Univ Catania, Dept Clin & Expt Med, Via S Sofia 78, I-95123 Catania, Italy
来源：
MOLECULES | 2021年 / 26卷 / 09期
关键词：
resveratrol; human male fertility; sperm parameters; cryopreservation; ACTIVATED PROTEIN-KINASE; CELLS; ESTROGEN; CANCER; BENZO(A)PYRENE; APOPTOSIS; COMPOUND; QUALITY; MEN;
D O I：
10.3390/molecules26092495
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Resveratrol (RSV) (3,4 ',5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer's disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore, this review evaluated the effects of RSV on human male fertility and the mechanisms through which this polyphenol could act on human spermatozoa.
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页数：10
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