A non-enzyme cascade amplification strategy for colorimetric assay of disease biomarkers

被引：26

作者：

Li, Jiuxing ^{[1
]}

Gao, Zhuangqiang ^{[1
,2
]}

Ye, Haihang ^{[1
]}

Wan, Shulin ^{[1
]}

Pierce, Meghan ^{[3
]}

Tang, Dianping ^{[2
]}

Xia, Xiaohu ^{[1
]}

机构：

[1] Michigan Technol Univ, Dept Chem, Houghton, MI 49931 USA

[2] Fuzhou Univ, Dept Chem, Collaborat Innovat Ctr Detect Technol Haixi Food, Key Lab Anal & Detect Food Safety,Fujian Prov & M, Fuzhou 350108, Fujian, Peoples R China

[3] Michigan Technol Univ, Dept Chem Engn, Houghton, MI 49931 USA

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 65期

基金：

美国国家科学基金会;

关键词：

ENHANCED RAMAN-SCATTERING; PEROXIDASE-LIKE ACTIVITY; ULTRASENSITIVE DETECTION; SIGNAL AMPLIFICATION; GOLD NANOPARTICLES; DNA; IMMUNOASSAY; ELISA; PROTEIN; CANCER;

D O I：

10.1039/c7cc04521b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A non-enzyme cascade amplification strategy, based on the dissolution of Ag nanoparticles and a Pt nanocube-catalyzed reaction, for colorimetric assay of disease biomarkers was developed. This strategy overcomes the intrinsic limitations of enzymes involved in conventional enzymatic amplification techniques, thanks to the utilization of noble-metal nanostructures with superior properties.

引用

页码：9055 / 9058

页数：4

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