Diffusion tensor imaging in the normal breast: influences of fibroglandular tissue composition and background parenchymal enhancement

被引:13
|
作者
Plaza, Michael Jonathan [1 ]
Morris, Elizabeth A. [1 ]
Thakur, Sunitha B. [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Radiol, 300 East 66th St, New York, NY 10065 USA
关键词
Diffusion; Tensor; Breast; MRI; DTI; MRI; DENSITY; METAANALYSIS; PARAMETERS; LESIONS; CANCER; RISK;
D O I
10.1016/j.clinimag.2015.12.001
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objective: To evaluate effects of fibroglandular tissue (FGT) composition and background parenchymal enhancement (BPE) on diffusion tensor imaging (DTI) parameters in normal breast tissue. Methods: DTI analysis was performed on 35 breasts with regions of interest drawn to include only normal tissue. Breasts were dichotomized by FGT composition and by BPE; DTI parameters were compared. Results: The lambda(1) principal diffusion coefficient was lower in breasts with moderate/marked BPE versus those with minimal/mild BPE (P=.039). All other parameters were unaffected. Conclusion: lambda(1) is sensitive to differences in BPE within normal breast tissue that should be taken into account in DTI evaluation. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:506 / 511
页数:6
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