Two Novel Mg (II) and Ho (III) Complexes Based on the Same Ligand Inhibit Growth of Human Lung Cancer Cells

被引：0
|
作者：
Xu, Yong [1 ]
Li, Jie [2 ]
机构：
[1] Zhejiang Univ, Coll Med, Sir Run Run Shaw Hosp, Dept Thorac Surg, Hangzhou, Zhejiang, Peoples R China
[2] Ningbo 2 Hosp, Dept Thorac Surg, Ningbo, Zhejiang, Peoples R China
来源：
LATIN AMERICAN JOURNAL OF PHARMACY | 2018年 / 37卷 / 05期
关键词：
anticancer activity; four-connected; metal-organic; METAL-ORGANIC FRAMEWORK;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Two new three-dimensional (3D) metal-organic frameworks, namely {[Mg-3(DTDN)(3)(H2O)(6)] (DMF)(2)}(n) (1, H2DTDN = 6,6'-dithiodinicotinic acid) and {[Ho-2(DTDN)(3)(H2O)(5)]center dot 7H(2)O}(n) (2) have been successfully prepared under solvothermal or hydrothermal conditions. The analysis results show that complex 1 is a 2-fold interpenetrated framework structure with a hxg topological network and complex 2 features a 3-D network with an uncommon twofold interpenetrating four-connected CdSO4 structure. In addition, in vitro anticancer activities of compounds 1 and 2 on four human lung cancer cell lines (H1299, MSTO-211H, PC9 and A549) was further determined.
引用
收藏
页码：1056 / 1060
页数：5
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