ReCSiP: An FPGA-based general-purpose biochemical simulator

被引:7
|
作者
Osana, Yasunori [1 ]
Yoshimi, Masato
Iwaoka, Yow
Kojima, Toshinori
Nishikawa, Yuri
Funahashi, Akira
Hiroi, Noriko
Shibata, Yuichiro
Iwanaga, Naoki
Kitano, Hiroaki
Amano, Hideharu
机构
[1] Keio Univ, Fac Sci & Technol, Dept Biosci & Informat, Yokohama, Kanagawa 223, Japan
[2] Keio Univ, Grad Sch Sci & Technol, Yokohama, Kanagawa 223, Japan
[3] ERATO, SORST, Japan Sci & Technol, Kitano Symbiot Syst Project, Tokyo 150, Japan
[4] Nagasaki Univ, Dept Comp & Informat Sci, Nagasaki 852, Japan
[5] Keio Univ, Fac Sci & Technol, Dept Informat & Comp Sci, Yokohama, Kanagawa 223, Japan
关键词
FPGA; biochemical simulations; ordinary differential equations; rate-law functions; Runge-Kutta method;
D O I
10.1002/ecjb.20370
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Mathematical modeling and simula tion of cellular systems are essential to modern biological researches. However, simulating with software-based simulators on general-purpose microprocessors cannot provide enough throughput. ReCSiP is an FPGA-based solution for biochemical simulation and parameter scanning. This paper describes its design and hardware implementation. With Xilinx's XC2VP70-5, this method achieved 50- to 80-fold speed-up compared to Intel's Pentium4 processor. (c) 2007 Wiley Periodicals, Inc.
引用
收藏
页码:1 / 10
页数:10
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