Poly(ADP-ribose) polymerase (PARP) inhibition and cytoprotection using novel, potent isoindolinone-inhibitors of PARP

被引:0
|
作者
Baloglu, E [1 ]
Jagtap, P [1 ]
Mabley, JG [1 ]
Salzman, AL [1 ]
Szabo, C [1 ]
Southan, GJ [1 ]
机构
[1] Inotek Pharmaceut Crop, Beverly, MA 01915 USA
来源
FASEB JOURNAL | 2003年 / 17卷 / 05期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:A1360 / A1360
页数:1
相关论文
共 50 条
  • [21] Poly(ADP-ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer (Review)
    Wiggans, Alison J.
    Cass, Gemma K. S.
    Bryant, Andrew
    Lawrie, Theresa A.
    Morrison, Jo
    [J]. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2022, (02):
  • [22] Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis
    Tentori, Lucio
    Lacal, Pedro Miguel
    Muzi, Alessia
    Dorio, Annalisa Susanna
    Leonetti, Carlo
    Scarsella, Marco
    Ruffini, Federica
    Xu, Weizheng
    Min, Wokee
    Stoppacciaro, Antonella
    Colarossi, Cristina
    Wang, Zhao-Qi
    Zhang, Jie
    Graziani, Grazia
    [J]. EUROPEAN JOURNAL OF CANCER, 2007, 43 (14) : 2124 - 2133
  • [23] Do poly(ADP-ribose) polymerase (PARP) inhibitors affect myocardial metabolism?
    Kiss, G. Y.
    Deres, P.
    Hanto, K.
    Bognar, E.
    Bartha, E.
    Sumegi, B.
    Berente, Z.
    [J]. EUROPEAN HEART JOURNAL, 2006, 27 : 410 - 410
  • [24] 'PARP'ing fibrosis: repurposing poly (ADP ribose) polymerase (PARP) inhibitors
    Rao, Pooja Dhileepkumar
    Sankrityayan, Himanshu
    Srivastava, Anjali
    Kulkarni, Yogesh A.
    Mulay, Shrikant R.
    Gaikwad, Anil Bhanudas
    [J]. DRUG DISCOVERY TODAY, 2020, 25 (07) : 1253 - 1261
  • [25] Role of poly (ADP-ribose) polymerase (PARP) in diabetic nephropathy
    Susztak, K
    Szabó, C
    Biser, A
    Xiao, CY
    Benk, R
    Bottinger, E
    [J]. AMERICAN JOURNAL OF KIDNEY DISEASES, 2006, 47 (04) : A57 - A57
  • [27] Discovery and SAR of novel, potent and selective hexahydrobenzonaphthyridinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)
    Torrisi, Caterina
    Bisbocci, Monica
    Ingenito, Raffaele
    Ontoria, Jesus M.
    Rowley, Michael
    Schultz-Fademrecht, Carsten
    Toniatti, Carlo
    Jones, Philip
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (02) : 448 - 452
  • [28] Rationale for Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Combination Therapy with Camptothecins or Temozolomide Based on PARP Trapping versus Catalytic Inhibition
    Murai, Junko
    Zhang, Yiping
    Morris, Joel
    Ji, Jiuping
    Takeda, Shunichi
    Doroshow, James H.
    Pommier, Yves
    [J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, 349 (03): : 408 - 416
  • [29] Substituted uracil derivatives as potent inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)
    Steinhagen, H
    Gerisch, M
    Mittendorf, J
    Schlemmer, KH
    Albrecht, B
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2002, 12 (21) : 3187 - 3190
  • [30] Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors
    Faraoni, Isabella
    Graziani, Grazia
    [J]. CANCERS, 2018, 10 (12):