Aberrations in Lipid Expression and Metabolism in Psoriasis

被引：59

作者：

Nowowiejska, Julia ^{[1
]}

Baran, Anna ^{[1
]}

Flisiak, Iwona ^{[1
]}

机构：

[1] Med Univ Bialystok, Dept Dermatol & Venereol, Zurawia 14 St, PL-15540 Bialystok, Poland

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2021年 / 22卷 / 12期

关键词：

psoriasis; lipids; cholesterol; triglycerides; fatty acids; lipoprotein; CARDIOVASCULAR RISK; LIPOPROTEIN; PATHOGENESIS; CHOLESTEROL; VULGARIS; OBESITY; IL-17;

D O I：

10.3390/ijms22126561

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Psoriasis (PSO) is a common skin disease that affects about 1%-3% of the general population. It is a great medical, social and economic burden since PSO is associated with many comorbidities, of which the most common are cardiometabolic disorders. Psoriatic patients suffer more frequently from obesity, dyslipidemia, atherosclerosis, and nonalcoholic fatty liver disease. Research shows that lipid expression and metabolism disorders are present more often in such patients. This review focuses on a variety of aberrations in lipids in the skin, blood, and adipose tissue in psoriatic patients and their multifactorial impact on the pathogenesis of psoriasis.

引用

页数：11

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