Process development in biotechnology -: A re-evaluation

被引：6
|
作者：
Schügerl, K [1 ]
机构：
[1] Leibniz Univ Hannover, Inst Chem Tech, D-30167 Hannover, Germany
来源：
ENGINEERING IN LIFE SCIENCES | 2005年 / 5卷 / 01期
关键词：
D O I：
10.1002/elsc.200402166
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
This review considers some process development problems in biotechnology and presents examples of solutions, which were developed in cooperation with industrial partners. These processes include the production of restriction endonuclease EcoRI by recombinant Escherichia coli, which is toxic to the cell, penicillin V by Penicillium chrysogenum, xylanase by Aspergillus awamori, cephalosporin C by Acremonium chrysogenum, erythritol by Moniliella tomentosa var pollinis, and alkaline serine protease by Bacillus licheniformis. Special attention is given to the practical aspects of product development.
引用
收藏
页码：15 / 28
页数：14
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