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De Novo CD5+ Primary Gastrointestinal Diffuse Large B-Cell Lymphoma: Challenges With Treatment and Clinical Course
被引:1
|作者:
Ramachandran, Preethi
[1
]
Sahni, Sonu
[1
]
Wang, Jen C.
[1
]
机构:
[1] Brookdale Univ Hosp & Med Ctr, Brooklyn, NY 11212 USA
来源:
关键词:
DLBCL;
gastrointestinal lymphoma;
CD5+ lymphoma;
B-cell lymphoma;
small bowel lymphoma;
CD5(+);
EXPRESSION;
TUMORS;
D O I:
10.1177/2324709619893546
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
The gastrointestinal tract is a common extranodal site for lymphomas. However, primary gastrointestinal lymphomas are rare. Diffuse large B-cell lymphomas (DLBCL) are the most commonly encountered type in the gastrointestinal tract. Most of the DLBCL are CD5 negative. CD5+ DLBCL is very rare and a poor prognostic subtype of lymphoma. We report a rare case of primary small bowel CD5+ DLBCL that evolved from being a localized low International Prognostic Index-scored disease into an advanced and aggressive disease primarily dictated by the presence of CD5 antigen positivity.
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