Phytochemical and Pharmacological Properties of the Genus Melodinus - A Review

被引：23

作者：

Jiang, Jin-He ^{[1
,2
,3
]}

Zhang, Wu-Di ^{[1
]}

Chen, Ye-Gao ^{[2
]}

机构：

[1] Yunnan Normal Univ, Fac Energy & Environm Sci, Kunming 650500, Peoples R China

[2] Yunnan Normal Univ, Dept Chem, Kunming 650500, Peoples R China

[3] Yunnan Normal Univ, Dept Lib, Kunming 650500, Peoples R China

来源：

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH | 2015年 / 14卷 / 12期

关键词：

Melodinus; Indole alkaloids; Dimeric alkaloids; Cytotoxicity; Medicinal plants; MAGNETIC-RESONANCE-SPECTROSCOPY; NATURALLY-OCCURRING SUBSTANCES; CYTOTOXIC INDOLE ALKALOIDS; NEW-CALEDONIA; CRYSTAL-STRUCTURE; PLANTS; (+)-SCANDINE; RHAZICINE; LEAVES;

D O I：

10.4314/tjpr.v14i12.25

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Melodinus is an important genus comprising of approximately 53 species of medicinal plants (Apocynaceae). Some species have been used in Chinese folk medicine for the treatment of meningitis in children, rheumatic heart diseases, and diuresis, as well as a decongestive against migraine and sinusitis. This paper is a review of the literature up to May 2015 and describes 263 compounds from 69 articles, and includes chemical constituents isolated from Melodinus, mainly indole alkaloids, quinoline alkaloids, dimeric alkaloids, terpenoids and other compounds. It is also hoped that an overview of their cytotoxic characteristics will further the development of new anti-cancer agents.

引用

页码：2325 / 2344

页数：20

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