The review presents basic epidemiological, etiological, pathogenetic and clinical data concerning Parkinson's disease (PD). Recent theories are debated including Braak's pathological hypothesis of PD and the role of LRRK2 mutation in the pathogenesis of sporadic PD. In the clinical part of the review, current diagnostic procedures and therapeutical approaches are shown.
机构:
Cornell Univ, Dept Neurol & Neurosci, Weill Med Coll, New York, NY 10021 USACornell Univ, Dept Neurol & Neurosci, Weill Med Coll, New York, NY 10021 USA
Thomas, Bobby
Beal, M. Flint
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机构:
Cornell Univ, Dept Neurol & Neurosci, Weill Med Coll, New York, NY 10021 USACornell Univ, Dept Neurol & Neurosci, Weill Med Coll, New York, NY 10021 USA