Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats

被引:96
|
作者
Mukherjee, PK [1 ]
Saha, K [1 ]
Pal, M [1 ]
Saha, BP [1 ]
机构
[1] JADAVPUR UNIV,FAC ENGN & TECHNOL,DEPT PHARMACEUT TECHNOL,CALCUTTA 700032,W BENGAL,INDIA
关键词
Nelumbo nucifera; rhizome; antidiabetic activity;
D O I
10.1016/S0378-8741(97)00107-4
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Oral administration of the ethanolic extract of rhizomes of Nelumbo nucifera markedly reduced the blood sugar level of normal, glucose-fed hyperglycemic and streptozotocin-induced diabetic rats, when compared with control animals. The extract improved glucose tolerance and potentiated the action of exogenously injected insulin in normal rats. When compared with tolbutamide, the extract exhibited activity of 73 and 67% of that of tolbutamide in normal and diabetic rats, respectively. (C) 1997 Elsevier Science Ireland Ltd.
引用
收藏
页码:207 / 213
页数:7
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