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An Update on Tourette Syndrome
被引:9
|作者:
Kimber, Thomas E.
[1
,2
]
机构:
[1] Royal Adelaide Hosp, Neurol Unit, Adelaide, SA 5000, Australia
[2] Univ Adelaide, Dept Med, Adelaide, SA 5005, Australia
关键词:
Movement disorders;
Tourette;
Deep brain stimulation;
Neuropsychiatric;
Tics;
DEEP BRAIN-STIMULATION;
DOUBLE-BLIND;
THALAMIC-STIMULATION;
BASAL GANGLIA;
CHILDREN;
PLACEBO;
LINKAGE;
ADOLESCENTS;
PIMOZIDE;
VOLUMES;
D O I:
10.1007/s11910-010-0118-2
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Recent advances in our understanding of the phenomenology, etiology, pathophysiology, and treatment of Tourette syndrome are discussed. Tourette syndrome appears to involve dysfunction of limbic and somatosensory "traffic" through the basal ganglia, within corticostriatal-thalamocortical circuits. Dynamic alterations in the balance of these inputs may dictate the manifestations (sensory, motor, affective, and behavioral) of the disorder at any given time. Individualized assessment and treatment are the keys to optimal treatment of this condition.
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页码:286 / 291
页数:6
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