Kolokosides A-D:: Triterpenoid glycosides from a Hawaiian isolate of Xylaria sp.

被引:48
|
作者
Deyrup, Stephen T.
Gloer, James B. [1 ]
O'Donnell, Kerry
Wicklow, Donald T.
机构
[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA
[2] USDA ARS, Natl Ctr Agr Utilizat Res, Mycotoxin Res Unit, Peoria, IL 61604 USA
来源
JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 03期
关键词
D O I
10.1021/np060546k
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Four new triterpenoid glycosides, kolokosides A-D (1-4), along with the known compound 19,20-epoxycytochalasin N, were isolated from cultures of a Hawaiian wood-decay fungus (Xylaria sp.). The structures and relative configurations of 1-4 were determined primarily by analysis of NMR data, and the absolute configuration of 1 was assigned by application of the exciton chirality method. Compound 1 exhibited activity against Gram-positive bacteria.
引用
收藏
页码:378 / 382
页数:5
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