A new HLA-DRB allele (DRB1*15014) identified in a Caucasian individual

被引：0
|
作者：
Czachurski, D [1 ]
Opelz, G [1 ]
Mytilineos, J [1 ]
机构：
[1] Heidelberg Univ, Inst Immunol, Dept Transplantat Immunol, D-69120 Heidelberg, Germany
来源：
HUMAN IMMUNOLOGY | 2003年 / 64卷 / 02期
关键词：
HLA-DRB1; PCR-SSP; sequence-based typing; DRB1*15014;
D O I：
10.1016/S0198-8859(02)00779-6
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Polymerase chain reaction with sequence specific primers subtyping of a DRB1*15 allele in a male 11-year-old German Caucasian and his father revealed a reaction pattern that did not agree with any known specificity, thus suggesting the existence of a novel allele. Sequence-based typing after allelic separation revealed the new allele human leukocyte antigen (HLA)-DRB1*15014. The sequence pattern of HLA-DRB1*15014 might have been generated as a result of two independent recombinations, most likely over several generations. (C) American Society for Histocompatibility and Immunogenetics, 2003. Published by Elsevier Science Inc.
引用
收藏
页码：310 / 313
页数：4
相关论文
共 50 条
  • [21] Identification of a new HLA-DRB1*13 allele (DRB1*1326) with a short DRB1*16 sequence
    Voorter, CEM
    deBruynGeraets, D
    Verduyn, W
    Schreuder, GMT
    vandenBergLoonen, EM
    TISSUE ANTIGENS, 1997, 49 (01): : 88 - 91
  • [22] A novel HLA-DRB1 allele, DRB1*0707
    Frison, S
    Poli, F
    Longhi, E
    Bianchi, P
    Baier, DM
    Scalamogna, M
    TISSUE ANTIGENS, 2003, 61 (03): : 259 - 260
  • [23] A new DRB1*15 allele (DRB1*1506) identified by sequence-based typing
    vandenBergLoonen, E
    Rani, R
    Singal, D
    Tilanus, M
    TISSUE ANTIGENS, 1997, 49 (02): : 189 - 191
  • [24] Description of a new DRB1*11 allele (DRB1*1132)
    Loiseau, P
    Loste, MN
    Lepage, V
    Schaeffer, V
    Lethielleux, P
    Tilanus, M
    van Der Zwan, AW
    Dubel, L
    Nigou, M
    Johanet, C
    Charron, D
    TISSUE ANTIGENS, 1998, 52 (04): : 402 - 404
  • [25] Report of a new DRB1*13 allele: DRB1*1336
    Jezek, DA
    Lower, FE
    Wagenknecht, DR
    Britton, RM
    Getty, RR
    Pulliam, JF
    McIntyre, JA
    Jennings, CD
    TISSUE ANTIGENS, 2001, 57 (06): : 548 - 550
  • [26] HLA-DRB1*1608: a new HLA-DRB1*16 allele with a short DRB1*03 sequence
    D. Reviron
    Anne Dormoy
    Marylise André
    Nadine Froelich
    Jean Roudier
    Marie Marthe Tongio
    Pierre Mercier
    Immunogenetics, 1997, 46 : 444 - 445
  • [27] Two newly identified HLA-DRB1 alleles: DRB1*1322 and DRB1*1327
    Karen J. Duran
    Hiroo Maeda
    Henny G. Otten
    Rene De Vries
    Geziena M. T. Schreuder
    M. G. J. Tilanus
    Immunogenetics, 1997, 46 : 442 - 443
  • [28] HLA-DRB1*1608: a new HLA-DRB1*16 allele with a short DRB1*03 sequence
    Reviron, D
    Dormoy, A
    Andre, M
    Froelich, N
    Roudier, J
    Tongio, MM
    Mercier, P
    IMMUNOGENETICS, 1997, 46 (05) : 444 - 445
  • [29] Two newly identified HLA-DRB1 alleles: DRB1*1322 and DRB1*1327
    Duran, KJ
    Maeda, H
    Otten, HG
    DeVries, R
    Schreuder, GMT
    Tilanus, MGJ
    IMMUNOGENETICS, 1997, 46 (05) : 442 - 443
  • [30] Nucleotide sequence of a new HLA-DRB1*11 allele (DRB1*1124)
    Schranz, P
    Seelig, R
    Seidl, C
    Renz, M
    IMMUNOGENETICS, 1996, 43 (04) : 242 - 243
12345